ArticlePloS one2012
Identification and characterization of novel genotoxic stress-inducible nuclear long noncoding RNAs in mammalian cells.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- Differences in gene expression in field populations of Wolbachia-infected Aedes aegypti mosquitoes with varying release histories in northern Australia.PLoS neglected tropical diseases · 2023Article
- Genome-Wide Identification of Long Noncoding RNA and Their Potential Interactors inInternational journal of molecular sciences · 2022Article
- Article
- Long noncoding RNA U90926 is crucial for herpes simplex virus type 1 proliferation in murine retinal photoreceptor cells.Scientific reports · 2020Article
- Article
- Transcriptome Analysis Suggests the Roles of Long Intergenic Non-coding RNAs in the Growth Performance of Weaned Piglets.Frontiers in genetics · 2019Article
- Genome-wide identification and differentially expression analysis of lncRNAs in tilapia.BMC genomics · 2018Article
- Long non-coding RNA PANDAR promotes melanoma cell invasion through regulating epithelial-mesenchymal transition.International journal of clinical and experimental pathology · 2018Article
- The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway.Cell death and differentiation · 2017Article
- Article
- Identification of Aedes aegypti Long Intergenic Non-coding RNAs and Their Association with Wolbachia and Dengue Virus Infection.PLoS neglected tropical diseases · 2016Article
- Environmental Health and Long Non-coding RNAs.Current environmental health reports · 2016Review
- Serum stress responsive gene EhslncRNA of Entamoeba histolytica is a novel long noncoding RNA.Scientific reports · 2016Article
- Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss.Genes & development · 2016Article
- lncRNAs in Stress Response.Current topics in microbiology and immunology · 2016Review
- Genome wide discovery of long intergenic non-coding RNAs in Diamondback moth (Plutella xylostella) and their expression in insecticide resistant strains.Scientific reports · 2015Article
- Contrasting expression patterns of coding and noncoding parts of the human genome upon oxidative stress.Scientific reports · 2015Article
- Altered expression of long non-coding RNAs during genotoxic stress-induced cell death in human glioma cells.Journal of neuro-oncology · 2015Article
- Long intergenic non-coding RNA induced by X-ray irradiation regulates DNA damage response signaling in the human bronchial epithelial BEAS-2B cell line.Oncology letters · 2015Article
- Identifcation of differentially expressed long non-coding RNAs in CD4+ T cells response to latent tuberculosis infection.The Journal of infection · 2014Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Whole transcriptome analyses have revealed a large number of novel transcripts including long and short noncoding RNAs (ncRNAs). Currently, there is great interest in characterizing the functions of the different classes of ncRNAs and their relevance to cellular processes. In particular, nuclear long ncRNAs may be involved in controlling various aspects of biological regulation, such as stress responses. By a combination of bioinformatic and experimental approaches, we identified 25 novel nuclear long ncRNAs from 6,088,565 full-length human cDNA sequences. Some nuclear long ncRNAs were conserved among vertebrates, whereas others were found only among primates. Expression profiling of the nuclear long ncRNAs in human tissues revealed that most were expressed ubiquitously. A subset of the identified nuclear long ncRNAs was induced by the genotoxic agents mitomycin C or doxorubicin, in HeLa Tet-off cells. There were no commonly altered nuclear long ncRNAs between mitomycin C- and doxorubicin-treated cells. These results suggest that distinct sets of nuclear long ncRNAs play roles in cellular defense mechanisms against specific genotoxic agents, and that particular long ncRNAs have the potential to be surrogate indicators of a specific cell stress.
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Registered trials
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