Trial reportEuropean journal of nuclear medicine and molecular imaging2012
PET/CT for staging and follow-up of pediatric nasopharyngeal carcinoma.
Trial report in European journal of nuclear medicine and molecular imaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of evidence for and against routine surveillance imaging after completing treatment for childhood extracranial solid tumors.Cancer medicine · 2020Pooled it
- PET/CT-guided treatment planning for paediatric cancer patients: a simulation study of proton and conventional photon therapy.The British journal of radiology · 2015Trial
- Article
- Enhanced direct joint attenuation and scatter correction of whole-body PET images via context-aware deep networks.Zeitschrift fur medizinische Physik · 2025Article
- An Uncommon Case of Pediatric Nasopharyngeal Carcinoma with Bone Metastases and Enchondromas Evaluated UsingMolecular imaging and radionuclide therapy · 2024Article
- The use of PET/MRI in radiotherapy.Insights into imaging · 2024Review
- SNMMI Procedure Standard/EANM Practice Guideline on PediatricJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021Article
- Tumor Blood Flow Is a Predictor of Radiotherapy Response in Patients With Nasopharyngeal Carcinoma.Frontiers in oncology · 2021Article
- Deep learning-based attenuation correction in the absence of structural information for whole-body positron emission tomography imaging.Physics in medicine and biology · 2020Article
- Treatment of Childhood Nasopharyngeal Carcinoma With Induction Chemotherapy and Concurrent Chemoradiotherapy: Results of the Children's Oncology Group ARAR0331 Study.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2019Article
- Update in pediatric nasopharyngeal undifferentiated carcinoma.The British journal of radiology · 2019Review
- Use of PET/CT instead of CT-only when planning for radiation therapy does not notably increase life years lost in children being treated for cancer.Pediatric radiology · 2015Article
- Magnetic Resonance Imaging Findings in Childhood Period Nasopharynx Cancer.Polish journal of radiology · 2015Article
- (18)F-FDG Uptake Characteristics in Differentiating Benign from Malignant Nasopharyngeal Lesions in Children.BioMed research international · 2015Article
- Detection of a metastatic lesion and tiny yolk sac tumors in two teenage patients by FDG-PET: report of two cases.Surgery today · 2014Article
- Role of (18)F-FDG PET/CT in pre and post treatment evaluation in head and neck carcinoma.World journal of radiology · 2014Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
purposeWhile FDG PET/CT for the evaluation of nasopharyngeal carcinoma (NPC) in adult patients has documented advantages and disadvantages compared with conventional imaging, to our knowledge, no studies of FDG PET/CT for the evaluation of NPC in pediatric patients have been performed. In this investigation, we studied the utility of FDG PET/CT in children with NPC.
methodsThe study group comprised 18 children with biopsy-proven NPC who underwent FDG PET/CT and MRI (total 38 pairs of images). All baseline and follow-up FDG PET/CT and MRI studies were independently reviewed for restaging of disease.
resultsThe concordance between FDG PET/CT and MRI in T, N, and overall staging was 29%, 64%, and 43%, respectively. Compared with MRI, FDG PET/CT yielded lower T and overall staging and showed less cervical and retropharyngeal lymphadenopathy. The concordance between follow-up FDG PET/CT and MRI was 79% overall and 100% 9 months after therapy. In patients who achieved complete remission, FDG PET/CT showed disease clearance 3-6 months earlier than MRI. There were no false-positive or false-negative FDG PET/CT scans during follow-up.
conclusionFDG PET/CT may underestimate tumor extent and regional lymphadenopathy compared with MRI at the time of diagnosis, but it helps to detect metastases and clarify ambiguous findings. FDG PET/CT is sensitive and specific for follow-up and enables earlier determination of disease remission. FDG PET/CT is a valuable imaging modality for the evaluation and monitoring of NPC in pediatric patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.