Evidence map›Paper›PMID 22532233›Full record

ArticlePediatric radiology2012

Prenatal diagnosis of fetal skeletal dysplasia with 3D CT.

Osamu Miyazaki, Gen Nishimura, Haruhiko Sago, Tetsuya Horiuchi, Satoshi Hayashi, Rika Kosaki

Abstract read
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In one paragraph

Article in Pediatric radiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Demonstration of Human Fetal Bone Morphology with MR Imaging: A Preliminary Study.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2020
    Article
  8. Article
  9. Article
  10. Article
  11. [Lethal osteogenesis imperfecta: antenatal diagnosis].The Pan African medical journal · 2016
    Article
  12. Article
  13. Advances in evaluating the fetal skeleton.International journal of women's health · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Osamu MiyazakiDepartment of Radiology, National Center for Child Health and Development, 2-10-1 Okura, Seatagaya-ku, Tokyo, 157-8535, Japan. osamu-m@rc4.so-net.ne.jp
Gen Nishimura
Haruhiko Sago
Tetsuya Horiuchi
Satoshi Hayashi
Rika Kosaki

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinical use of 3D CT for fetal skeletal malformations is controversial.

objectiveThe purpose of this study was to evaluate the efficacy of fetal 3D CT using three protocols with different radiation doses and through comparing findings between fetal CT and conventional postnatal radiographic skeletal survey. MATERIALS AND

methodsSeventeen fetuses underwent CT for suspected skeletal dysplasia. A relay of three CT protocols with stepwise dose-reduction were used over the study period. The concordance between the CT diagnosis and the final diagnosis was assessed. Ninety-three radiological findings identifiable on radiographs were compared with CT.

resultsFetal CT provided the correct diagnosis in all 17 fetuses, the detectability rate of cardinal findings was 93.5 %. In 59 % of the fetuses an US-based diagnosis was changed prenatally due to CT findings. The estimated fetal radiation dose in the final protocol was 3.4 mSv (50 %) of the initial protocol, and this dose reduction did not result in degraded image quality.

conclusionThe capability of fetal CT to delineate the skeleton was almost the same as that of postnatal skeletal survey. The perinatal management was altered due to these more specific CT findings, which aided in counseling and in the management of the pregnancy.

Indexed as

Bone Diseases, DevelopmentalFemaleHumansImaging, Three-DimensionalMalePregnancyPrenatal DiagnosisReproducibility of ResultsSensitivity and SpecificityTomography, X-Ray Computed

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.