ReviewEnvironmental science and pollution research international2012
Glutathione, glutathione S-transferase, and glutathione conjugates, complementary markers of oxidative stress in aquatic biota.
Review in Environmental science and pollution research international, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 194 citations in OpenAlex.
- Pooled it
- Metal-Driven Biochemical and Physiological Stress in Fish Inhabiting an Urban Coastal Lagoon: Evidence from an Integrated Multibiomarker Approach.Biological trace element research · 2026Article
- Antioxidant Compounds in Microalgae and Cyanobacteria: A Sustainable Source of Bioactive Molecules.Marine drugs · 2026Review
- DietaryAnimals : an open access journal from MDPI · 2026Article
- Short-Term Dietary Exposure to Ochratoxin A, Zearalenone or Fumonisins in Broiler Chickens: Effects on Cytochrome P450 Enzymes, Drug Transporters and Antioxidant Defence Systems.Foods (Basel, Switzerland) · 2025Article
- Physiological responses and histological alterations induced by pollution in the Nile tilapia from the Rosetta branch of the River Nile, Egypt.Scientific reports · 2025Article
- Impact of climate change driven freshening, warming, and ocean acidification on the cellular metabolism of Atlantic Cod (Gadus morhua).Scientific reports · 2025Article
- Induced swimming reduced stress and modulated immune response and antioxidant status in juvenile rainbow trout (Oncorhynchus mykiss).Fish physiology and biochemistry · 2025Article
- Metabolic Disruptions in Zebrafish Induced by α-Cypermethrin: A Targeted Metabolomics Study.Toxics · 2025Article
- Negative Effect of Gst-35 on the Health Span of Caenorhabditis elegans Through Lysosomal Dysfunction via the Pmk-1 and Skr Genes.Aging cell · 2025Article
- Article
- Review of Allelopathy in Green Tides: The Case ofBiology · 2024Review
- Physiological responses of Atlantic cod to climate change indicate that coastal ecotypes may be better adapted to tolerate ocean stressors.Scientific reports · 2024Article
- The heat is on: sensitivity of goldsinny wrasse to global climate change.Conservation physiology · 2024Article
- Article
- African Jointfir (Food science & nutrition · 2023Article
- Targeted metabolomics characterizes metabolite occurrence and variability in stable freshwater mussel populations.Conservation physiology · 2023Article
- Contaminants of emerging concern in the Maumee River and their effects on freshwater mussel physiology.PloS one · 2023Article
- Oxidative Stress Parameters and Morphological Changes in Japanese Medaka (Life (Basel, Switzerland) · 2022Article
- All for one: changes in mitochondrial morphology and activity during syncytial oogenesis†.Biology of reproduction · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Contaminants are ubiquitous in the environment and their impacts are of increasing concern due to human population expansion and the generation of deleterious effects in aquatic species. Oxidative stress can result from the presence of persistent organic pollutants, metals, pesticides, toxins, pharmaceuticals, and nanomaterials, as well as changes in temperature or oxygen in water, the examined species, with differences in age, sex, or reproductive cycle of an individual. The antioxidant role of glutathione (GSH), accompanied by the formation of its disulfide dimer, GSSG, and metabolites in response to chemical stress, are highlighted in this review along with, to some extent, that of glutathione S-transferase (GST). The available literature concerning the use and analysis of these markers will be discussed, focusing on studies of aquatic organisms. The inclusion of GST within the suite of biomarkers used to assess the effects of xenobiotics is recommended to complement that of lipid peroxidation and mixed function oxygenation. Combining the analysis of GSH, GSSG, and conjugates would be beneficial in pinpointing the role of contaminants within the plethora of causes that could lead to the toxic effects of reactive oxygen species.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.