ArticleInternational urogynecology journal2012
Two-year follow-up of an open-label multicenter study of polyacrylamide hydrogel (Bulkamid®) for female stress and stress-predominant mixed incontinence.
Article in International urogynecology journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02538991 (TVT Versus Bulkamid®-Injections in Treatment of Stress Urinary Incontinence - Patient Satisfaction and Complications of the Treatment), which is not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
TVT Versus Bulkamid®-Injections in Treatment of Stress Urinary Incontinence - Patient Satisfaction and Complications of the Treatment
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Adverse Events Associated with Nonsurgical Treatments for Urinary Incontinence in Women: a Systematic Review.Journal of general internal medicine · 2019Pooled it
- Polyacrylamide hydrogel (Bulkamid®) for stress urinary incontinence in women: a systematic review of the literature.International urogynecology journal · 2016Pooled it
- The efficacy and safety of urethral injection therapy for urinary incontinence in women: a systematic review.Clinics (Sao Paulo, Brazil) · 2016Pooled it
- Quality of life and sexual function after tension-free vaginal tape and polyacrylamide hydrogel injection for primary stress urinary incontinence: 3-year follow-up from a randomized clinical trial.International urogynecology journal · 2023Trial
- Quality of life and sexual function after TVT surgery versus Bulkamid injection for primary stress urinary incontinence: 1 year results from a randomized clinical trial.International urogynecology journal · 2021Trial
- Early Feasibility Study to Evaluate the Viveve System for Female Stress Urinary Incontinence: Interim 6-Month Report.Journal of women's health (2002) · 2020Trial
- Hydrogel-Based Therapies for Female Stress Urinary Incontinence: From Bulking Agents to Regenerative Platforms-A Narrative Review.Current urology reports · 2026Review
- Intraurethral cross-linked hyaluronic acid/dextranomer (DEXSUI®) injection versus mid-urethral sling for stress urinary incontinence: a comparative short-term outcome analysis.The Canadian journal of urology · 2026Article
- Predictive Measurement of Urethral Mobility for Successful Transurethral Bulkamid Application in Women with Stress Urinary Incontinence.Journal of clinical medicine · 2025Article
- Up-to-Date Procedures in Female Stress Urinary Incontinence Surgery: A Concise Review on Bulking Agents Procedures.Medicina (Kaunas, Lithuania) · 2022Review
- Combination therapy with botulinum toxin and bulking agent-An efficient, sustainable, and safe method to treat elderly women with mixed urinary incontinence.Neurourology and urodynamics · 2021Article
- Urethral bulking agents: a retrospective review of primary versus salvage procedure outcomes.World journal of urology · 2021Article
- A 12-month feasibility study to investigate the effectiveness of cryogen-cooled monopolar radiofrequency treatment for female stress urinary incontinence.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2020Article
- Article
- Particulate Versus Non-Particulate Bulking Agents In The Treatment Of Stress Urinary Incontinence.Research and reports in urology · 2019Review
- Bulkamid (PAHG) in mixed urinary incontinence: What is the outcome?International urogynecology journal · 2017Article
- A national population-based cohort study of urethral injection therapy for female stress and mixed urinary incontinence: the Danish Urogynaecological Database, 2007-2011.International urogynecology journal · 2017Article
- Periurethral bulking agents for female stress urinary incontinence in Canada.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2017Review
- Durability, safety and efficacy of polyacrylamide hydrogel (Bulkamid(®)) in the management of stress and mixed urinary incontinence: three year follow up outcomes.Central European journal of urology · 2015Article
- Urolastic for the treatment of women with stress urinary incontinence: 24-month follow-up.Central European journal of urology · 2015Article
Corrections and comments
- Commented on by
Authors and funding
5 authors.
Funding
Abstract
introduction and hypothesisPolyacrylamide hydrogel (PAHG, Bulkamid®) is a promising urethral bulking agent. This article presents the 2-year follow-up results of a multicenter study of PAHG injections for treating stress and stress-predominant mixed urinary incontinence.
methodsSubmucosal injection of PAHG was performed in 135 women with urinary incontinence, with subjective and objective assessment of the efficacy and safety 24 months postinjection.
resultsAt 24 months, the subjective responder rate was 64 % (a statistically non-significant reduction from 67 % at 12 months). The decreased number of incontinence episodes and urine leakage were maintained compared with the result from the 12-month evaluations, as were objective result rates and quality of life data. No safety issues occurred.
conclusionsPAHG is an effective and safe treatment option for women with stress-predominant mixed urinary incontinence, with maintained medium-term responder rates.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.