Evidence map›Paper›PMID 22531050›Full record

ArticleBMC women's health2012

Hypovitaminosis D and prevalent asymptomatic vertebral fractures in Moroccan postmenopausal women.

Abdellah El Maghraoui, Zhor Ouzzif, Aziza Mounach, Asmaa Rezqi, Lahsen Achemlal, Ahmed Bezza, Saida Tellal, Mohamed Dehhaoui, Imad Ghozlani

Open access · goldAbstract read
In one paragraph

Article in BMC women's health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 4 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Osteoporotic hip and vertebral fractures in the Arab region: a systematic review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Pooled it
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  4. Is vitamin D deficiency a major global public health problem?The Journal of steroid biochemistry and molecular biology · 2014
    Pooled it
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  16. Higher serum sclerostin levels and insufficiency of vitamin D are strongly associated with vertebral fractures in hemodialysis patients: a case control study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Abdellah El MaghraouiRheumatology Department, Military Hospital Mohammed V, PO Box 1018 Rabat, Morocco. aelmaghraoui@gmail.com
Zhor Ouzzif
Aziza Mounach
Asmaa Rezqi
Lahsen Achemlal
Ahmed Bezza
Saida Tellal
Mohamed Dehhaoui
Imad Ghozlani
Mohammed V University · MAInstitut Agronomique et Vétérinaire Hassan II · MAMilitary Hospital · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypovitaminosis D is associated to accentuated bone loss. However, association between osteoporotic vertebral fractures (VFs) and vitamin D status has not been clearly established.

objectiveTo determine serum vitamin D status and to assess the association of vitamin D status with bone mineral density (BMD) and asymptomatic VFs prevalence using vertebral fracture assessment (VFA) in a cohort of Moroccan menopausal women.

methodsfrom June to September 2010, 178 menopausal women 50 years old and over were enrolled in this cross-sectional study. The mean ± SD (range) age, weight, height and BMI were 58.8 ± 8.2 (50 to 79) years, 73.2 ± 13.8 (35 to 119) Kgs, 1.56 ± 0.06 (1.43 - 1.79) m and 29.8 ± 5.9 (17.5 - 49.8) kg/m2, respectively. VFA images and scans of the lumbar spine and proximal femur were obtained using a GE Healthcare Lunar Prodigy densitometer. VFs were defined using a combination of Genant semiquantitative approach and morphometry. Serum levels of 25-hydroxyvitamin D (25(OH)D) were measured.

resultsAmong the 178 women, 45 (25.2%) had densitometric osteoporosis, and on VFA, VFs (grade 2 or 3) were detected in 20.2% while grade 1 were identified in 33.1%. The mean values of serum levels of 25(OH)D were 15.8 ± 11.6 ng/ml (range: 3.0 - 49.1) with 152 patients (85.3%) having levels <30 ng/ml (insufficiency) and 92 (51.6%) <10 ng/ml (deficiency). Stepwise regression analysis showed that presence of VFs was independently related to age, 25(OH)D and densitometric osteoporosis.

conclusionour study shows that advanced age, hypovitaminosis D and osteoporosis are independent risk factors for asymptomatic VFs in Moroccan postmenopausal women.

Indexed as

Bone DensityPostmenopauseWomen's HealthAgedAge FactorsCohort StudiesCross-Sectional StudiesFemaleHumansMiddle AgedMoroccoOsteoporosisPrevalenceRisk FactorsSpinal FracturesVitamin D25-hydroxyvitamin DVitamin D

Identifiers

PMID22531050
PMCPMC3403946
OpenAlexW2108788145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.