SynthesisActa orthopaedica2012
RSA prediction of high failure rate for the uncoated Interax TKA confirmed by meta-analysis.
Synthesis in Acta orthopaedica, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The accuracy and precision of CT-RSA in arthroplasty: a systematic review and meta-analysis.Acta orthopaedica · 2025Pooled it
- 6-month migration sufficient for evaluation of total knee replacements: a systematic review and meta-analysis.Acta orthopaedica · 2023Pooled it
- Is the French Paradox cementing philosophy superior to the standard cementing? A randomized controlled radiostereometric trial and comparative analysis.The bone & joint journal · 2022Trial
- A randomized controlled trial comparing tibial migration of the ATTUNE cemented cruciate-retaining knee prosthesis with the PFC-sigma design.The bone & joint journal · 2020Trial
- Trabecular metal tibial knee component still stable at 10 years.Acta orthopaedica · 2016Trial
- A translational murine model of aseptic loosening with osseointegration failure.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024Article
- Highlighting the advantages and benefits of cementless total knee arthroplasty (Review).Experimental and therapeutic medicine · 2022Review
- Comparable mid-term revision rates of primary cemented and cementless total knee arthroplasties in 201,211 cases in the Dutch Arthroplasty Register (2007-2017).Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2021Article
- Cementing technique for total knee arthroplasty in cadavers using a pastry bone cement.Journal of orthopaedic surgery and research · 2021Article
- Inhibition of PAD4 mediated neutrophil extracellular traps prevents fibrotic osseointegration failure in a tibial implant murine model : an animal study.The bone & joint journal · 2021Article
- Does Knee Prosthesis Survivorship Improve When Implant Designs Change? Findings from the Australian Orthopaedic Association National Joint Replacement Registry.Clinical orthopaedics and related research · 2020Article
- The era of phased introduction of new implants.Bone & joint research · 2016Article
- Cementless total knee arthroplasty.Annals of translational medicine · 2016Review
- Special Review: Accelerating fracture repair in humans: a reading of old experiments and recent clinical trials.BoneKEy reports · 2013Review
- Radiostereometry and new prostheses.Acta orthopaedica · 2012Article
- Gap patterns and radiographic follow-up of newer-generation cementless total knee arthroplasty designs.Canadian journal of surgery. Journal canadien de chirurgieArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeIn a previous radiostereometric (RSA) trial the uncoated, uncemented, Interax tibial components showed excessive migration within 2 years compared to HA-coated and cemented tibial components. It was predicted that this type of fixation would have a high failure rate. The purpose of this systematic review and meta-analysis was to investigate whether this RSA prediction was correct. MATERIALS AND
methodsWe performed a systematic review and meta-analysis to determine the revision rate for aseptic loosening of the uncoated and cemented Interax tibial components.
results3 studies were included, involving 349 Interax total knee arthroplasties (TKAs) for the comparison of uncoated and cemented fixation. There were 30 revisions: 27 uncoated and 3 cemented components. There was a 3-times higher revision rate for the uncoated Interax components than that for cemented Interax components (OR = 3; 95% CI: 1.4-7.2).
interpretationThis meta-analysis confirms the prediction of a previous RSA trial. The uncoated Interax components showed the highest migration and turned out to have the highest revision rate for aseptic loosening. RSA appears to enable efficient detection of an inferior design as early as 2 years postoperatively in a small group of patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.