Trial reportBMC nephrology2012
The association of moderate renal dysfunction with impaired preference-based health-related quality of life: third Korean national health and nutritional examination survey.
Trial report in BMC nephrology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Exploring factors associated with Kidney Disease Quality of Life in patients with advanced chronic kidney disease: the Reach-J CKD cohort study.Clinical and experimental nephrology · 2025Article
- Investigating the relationship between FRailty And Quality of LIfe in patients with heart faiLure and CKD (FRAIL study).ESC heart failure · 2024Article
- Magnesium in Kidney Function and Disease-Implications for Aging and Sex-A Narrative Review.Nutrients · 2023Review
- Health-Related Quality of Life according to Renal Function: Results from a Nationwide Health Interview and Examination Survey.Kidney & blood pressure research · 2022Article
- Health-Related Quality of Life in People Across the Spectrum of CKD.Kidney international reports · 2020Article
- Chronic kidney disease attenuates the impact of obesity on quality of life.Scientific reports · 2020Article
- Article
- Association of anemia and mineral and bone disorder with health-related quality of life in Asian pre-dialysis patients.Health and quality of life outcomes · 2016Article
- Living with moderate to severe renal failure from the perspective of patients.BMC nephrology · 2016Article
- Family income is associated with quality of life in patients with chronic kidney disease in the pre-dialysis phase: a cross sectional study.Health and quality of life outcomes · 2015Article
- Health-Related Quality of Life and Cardiovascular Disease Risk in Korean Adults.Korean journal of family medicine · 2015Article
- Influence of frailty on health-related quality of life in pre-dialysis patients with chronic kidney disease in Korea: a cross-sectional study.Health and quality of life outcomes · 2015Article
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOnly a few large-scale studies have investigated the association between health-related quality of life (HRQOL) and renal function. Moreover, the HRQOL of patients with moderate renal dysfunction is frequently underestimated by healthcare providers. This study assessed the impact of renal function on preference-based HRQOL in Korean adult population.
methodsWe analyzed data for 5,555 adults from the 3(rd) Korean National Health and Nutritional Examination Survey 2005. The EuroQol-5D (EQ-5D) utility score was used to evaluate HRQOL. The study subjects were stratified into three groups based on their estimated glomerular filtration rates (eGFRs): ≥ 90.0, 60.0-89.9 and 30.0-59.9 mL/min/1.73 m(2). Individuals with advanced renal dysfunction were excluded from the analysis.
resultsThe proportions of participants who reported problems in each of the five EQ-5D dimensions increased significantly with decreasing eGFR. However, a significant decrease in the EQ-5D utility score was observed among participants with an eGFR of 30.0-59.9 mL/min/1.73 m(2). Participants with an eGFR of 30.0-59.9 mL/min/1.73 m(2) had an almost 1.5-fold higher risk of impaired health utility (the lowest quartile of EQ-5D utility score) compared with those participants with eGFRs ≥ 90.0 mL/min/1.73 m(2), after adjustment for age, gender, health-related behaviors, socioeconomic and psychological variables, and other comorbidities. Among the five dimensions of the EQ-5D, an eGFR of 30.0-59.9 mL/min/1.73 m(2) was an independent determinant of self-reported problems in the mobility and pain/discomfort dimensions.
conclusionsAlthough age affects the association between renal dysfunction and the EQ-5D, moderate renal dysfunction seems to be an important determinant of impaired health utility in a general population and may affect the mobility and pain/discomfort dimensions of health utility.
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