Evidence map›Paper›PMID 22529921›Full record

ArticlePloS one2012

Tinnitus: distinguishing between subjectively perceived loudness and tinnitus-related distress.

Elisabeth Wallhäusser-Franke, Joachim Brade, Tobias Balkenhol, Roberto D'Amelio, Andrea Seegmüller, Wolfgang Delb

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 81 citations in OpenAlex.

  1. Trial
  2. Focal tDCS of auditory cortex in chronic tinnitus: A randomized controlled mechanistic trial.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024
    Trial
  3. Trial
  4. Tinnitus in urban settings: insights into lifestyle and medical factors from the Hamburg City Health Study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
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  10. Tinnitus: Clinical Insights in Its Pathophysiology-A Perspective.Journal of the Association for Research in Otolaryngology : JARO · 2024
    Review
  11. Article
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  18. Tinnitus, sound intolerance, and mental health: the role of long-term occupational noise exposure.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Article
  19. Article
  20. Characteristics of tinnitus and factors influencing its severity.Therapeutic advances in chronic disease · 2022
    Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Elisabeth Wallhäusser-FrankeDepartment of Phoniatrics and Audiology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. elisabeth.wallhaeusser@medma.uni-heidelberg.de
Joachim Brade
Tobias Balkenhol
Roberto D'Amelio
Andrea Seegmüller
Wolfgang Delb
University Hospital Heidelberg · DEUniversity Medical Centre Mannheim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOverall success of current tinnitus therapies is low, which may be due to the heterogeneity of tinnitus patients. Therefore, subclassification of tinnitus patients is expected to improve therapeutic allocation, which, in turn, is hoped to improve therapeutic success for the individual patient. The present study aims to define factors that differentially influence subjectively perceived tinnitus loudness and tinnitus-related distress.

methodsIn a questionnaire-based cross-sectional survey, the data of 4705 individuals with tinnitus were analyzed. The self-report questionnaire contained items about subjective tinnitus loudness, type of onset, awareness and localization of the tinnitus, hearing impairment, chronic comorbidities, sleep quality, and psychometrically validated questionnaires addressing tinnitus-related distress, depressivity, anxiety, and somatic symptom severity. In a binary step-wise logistic regression model, we tested the predictive power of these variables on subjective tinnitus loudness and tinnitus-related distress.

resultsThe present data contribute to the distinction between subjective tinnitus loudness and tinnitus-related distress. Whereas subjective loudness was associated with permanent awareness and binaural localization of the tinnitus, tinnitus-related distress was associated with depressivity, anxiety, and somatic symptom severity.

conclusionsSubjective tinnitus loudness and the potential presence of severe depressivity, anxiety, and somatic symptom severity should be assessed separately from tinnitus-related distress. If loud tinnitus is the major complaint together with mild or moderate tinnitus-related distress, therapies should focus on auditory perception. If levels of depressivity, anxiety or somatic symptom severity are severe, therapies and further diagnosis should focus on these symptoms at first.

Indexed as

AdolescentAdultAgedAged, 80 and overComorbidityCross-Sectional StudiesDiagnosis, DifferentialFemaleHumansLogistic ModelsLoudness PerceptionMaleMiddle AgedRisk FactorsStress, PhysiologicalSurveys and Questionnaires

Identifiers

PMID22529921
PMCPMC3329489
OpenAlexW2118953939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.