ArticleFrontiers in neurology2012
Alzheimer's disease: a clinical practice-oriented review.
Article in Frontiers in neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Chronic schizophrenia versus Alzheimer's disease: neuroimaging perspectives on the late-life course of schizophrenia.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Alzheimer's Disease and Alzheimer's Disease-Related Dementias in African Americans: Focus on Caregivers.Healthcare (Basel, Switzerland) · 2023Review
- Article
- Is Aducanumab for LMICs? Promises and Challenges.Brain sciences · 2021Review
- Obesity and Diabetes Mediated Chronic Inflammation: A Potential Biomarker in Alzheimer's Disease.Journal of personalized medicine · 2020Review
- Beneficial Effects of Fingolimod in Alzheimer's Disease: Molecular Mechanisms and Therapeutic Potential.Neuromolecular medicine · 2019Review
- Learning using privileged information improves neuroimaging-based CAD of Alzheimer's disease: a comparative study.Medical & biological engineering & computing · 2019Article
- Mitochondrial integrity in neurodegeneration.CNS neuroscience & therapeutics · 2019Review
- Linking late life depression and Alzheimer's disease: mechanisms and resilience.Current behavioral neuroscience reports · 2019Article
- Towards Consensus on Essential Components of Physical Examination in Primary Care-based Memory Clinics.Canadian geriatrics journal : CGJ · 2018Article
- Mechanisms of Alzheimer's Disease Pathogenesis and Prevention: The Brain, Neural Pathology, N-methyl-D-aspartate Receptors, Tau Protein and Other Risk Factors.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2017Review
- Successful Object Encoding Induces Increased Directed Connectivity in Presymptomatic Early-Onset Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2017Article
- Overstimulation of the inhibitory nervous system plays a role in the pathogenesis of neuromuscular and neurological diseases: a novel hypothesis.F1000Research · 2016Article
- Retinal microvascular network attenuation in Alzheimer's disease.Alzheimer's & dementia (Amsterdam, Netherlands) · 2015Article
- Neural stem cells isolated from amyloid precursor protein-mutated mice for drug discovery.World journal of stem cells · 2013Article
- Circulating microRNAs: a novel class of potential biomarkers for diagnosing and prognosing central nervous system diseases.Cellular and molecular neurobiology · 2013Review
- The triggering receptor expressed on myeloid cells 2: "TREM-ming" the inflammatory component associated with Alzheimer's disease.Oxidative medicine and cellular longevity · 2013Review
- Cognitive impairment and dementia-an update.Frontiers in neurology · 2012Article
- Am I losing it?Journal of community hospital internal medicine perspectives · 2012Article
- Cognitive impairment and dementia in Parkinson's disease: clinical features, diagnosis, and management.Frontiers in neurology · 2012Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Investigation in the field of Alzheimer's disease (AD), the commonest cause of dementia, has been very active in recent years and it may be difficult for the clinician to keep up with all the innovations and to be aware of the implications they have in clinical practice. The authors, thus, reviewed recent literature on the theme in order to provide the clinician with an updated overview, intended to support decision-making on aspects of diagnosis and management. This article begins to focus on the concept of AD and on its pathogenesis. Afterward, epidemiology and non-genetic risk factors are approached. Genetics, including genetic risk factors and guidelines for genetic testing, are mentioned next. Recommendations for diagnosis of AD, including recently proposed criteria, are then reviewed. Data on the variants of AD is presented. First approach to the patient is dealt with next, followed by neuropsychological evaluation. Biomarkers, namely magnetic resonance imaging, single photon emission tomography, FDG PET, PiB PET, CSF tau, and Aβ analysis, as well as available data on their diagnostic accuracy, are also discussed. Factors predicting rate of disease progression are briefly mentioned. Finally, non-pharmacological and pharmacological treatments, including established and emerging drugs, are addressed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.