ArticleFrontiers in pharmacology2012
Endocannabinoid-dopamine interactions in striatal synaptic plasticity.
Article in Frontiers in pharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 77 citations in OpenAlex.
- Synchronous activation of striatal cholinergic interneurons induces local serotonin release.Nature communications · 2026Article
- Neurotrophin-3 Rescues Striatal Synaptic Plasticity in Model of Neurodegeneration by PLC Signaling Activation.CNS & neurological disorders drug targets · 2024Article
- Interplay between the Glymphatic System and the Endocannabinoid System: Implications for Brain Health and Disease.International journal of molecular sciences · 2023Review
- ABHD6 Controls Amphetamine-Stimulated Hyperlocomotion: Involvement of CBCannabis and cannabinoid research · 2022Article
- Striatal Indirect Pathway Dysfunction Underlies Motor Deficits in a Mouse Model of Paroxysmal Dyskinesia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- 2-Arachidonoylglycerol mobilization following brief synaptic stimulation in the dorsal lateral striatum requires glutamatergic and cholinergic neurotransmission.Neuropharmacology · 2022Article
- Roles of the Cannabinoid System in the Basal Ganglia in Parkinson's Disease.Frontiers in cellular neuroscience · 2022Review
- Caveolin-1 Expression in the Dorsal Striatum Drives Methamphetamine Addiction-Like Behavior.International journal of molecular sciences · 2021Article
- Modulating the Neuromodulators: Dopamine, Serotonin, and the Endocannabinoid System.Trends in neurosciences · 2021Review
- Dysfunction of the corticostriatal pathway in autism spectrum disorders.Journal of neuroscience research · 2020Review
- SCH23390 Reduces Methamphetamine Self-Administration and Prevents Methamphetamine-Induced Striatal LTD.International journal of molecular sciences · 2020Article
- Cannabis points to the synaptic pathology of mental disorders: how aberrant synaptic components disrupt the highest psychological functions .Dialogues in clinical neuroscience · 2020Review
- Cyclic AMP-dependent protein kinase and D1 dopamine receptors regulate diacylglycerol lipase-α and synaptic 2-arachidonoyl glycerol signaling.Journal of neurochemistry · 2020Article
- mGlu5 in GABAergic neurons modulates spontaneous and psychostimulant-induced locomotor activity.Psychopharmacology · 2020Article
- Cannabinoid CBNature medicine · 2019Article
- Claustrum circuit components for top-down input processing and cortical broadcast.Brain structure & function · 2018Article
- Dopamine-endocannabinoid interactions mediate spike-timing-dependent potentiation in the striatum.Nature communications · 2018Article
- Long-Term Plasticity in Amygdala Circuits: Implication of CB1-Dependent LTD in Stress.Molecular neurobiology · 2018Article
- Bidirectional and long-lasting control of alcohol-seeking behavior by corticostriatal LTP and LTD.Nature neuroscience · 2018Article
- Modulation of Spike-Timing Dependent Plasticity: Towards the Inclusion of a Third Factor in Computational Models.Frontiers in computational neuroscience · 2018Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The nigrostriatal dopaminergic system is implicated in action control and learning. A large body of work has focused on the contribution of this system to modulation of the corticostriatal synapse, the predominant synapse type in the striatum. Signaling through the D2 dopamine receptor is necessary for endocannabinoid-mediated depression of corticostriatal glutamate release. Here we review the known details of this mechanism and discuss newly discovered signaling pathways interacting with this system that ultimately exert dynamic control of cortical input to the striatum and striatal output. This topic is timely with respect to Parkinson's disease given recent data indicating changes in the striatal endocannabinoid system in patients with this disorder.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.