ArticlePLoS biology2012
FTIP1 is an essential regulator required for florigen transport.
Article in PLoS biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 142 papers, 1 of them a synthesis that pooled it.
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Who cites it
142 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A comparative meta-proteomic pipeline for the identification of plasmodesmata proteins and regulatory conditions in diverse plant species.BMC biology · 2022Pooled it
- Analysis of the synergistic effect between CiFTIP1 and CiFT in flowering regulation of citrus.Planta · 2026Article
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- In situ architecture of plasmodesmata in Physcomitrium patens resolved by cryo-electron tomography.Nature plants · 2026Article
- Genome-Wide Identification of theInternational journal of molecular sciences · 2026Article
- Differential methylation analysis of floral buds between two morphs unravels the contributions of key genes to flowering time in heterodichogamousHorticulture research · 2026Article
- Genome-Wide Identification and Expression Analysis of the PEBP Gene Family inPlants (Basel, Switzerland) · 2026Article
- Transcriptomic Analysis Provides Insights into Flowering in Precocious-FruitingPlants (Basel, Switzerland) · 2026Article
- QTL mapping of vernalization-insensitive and photoperiod-independent early flowering in yellow lupin (Frontiers in plant science · 2026Article
- Functional Characterization of Floral Gene Network Reveals a Critical FT1-AP1 Interaction in Flowering Regulation in Longan.Plants (Basel, Switzerland) · 2025Article
- Structural insights into AVR-Rmg8 recognition mechanisms by the wheat blast resistance gene Rmg8.Scientific reports · 2025Article
- Article
- QTL mapping and candidate gene identification of the full flowering date trait in olive trees (Olea Europaea L.).BMC plant biology · 2025Article
- Transcriptomic insights into gibberellin-3-mediated regulation of bud dormancy and metabolic transition in pitaya (Hylocereus polyrhizus).Plant cell reports · 2025Article
- A pair of readers of histone H3K4 methylation recruit Polycomb repressive complex 2 to regulate photoperiodic flowering.Nature communications · 2025Article
- The MADS-box gene CmAP1 promotes flowering and petal development in Chinese chestnut (Castanea mollissima).BMC plant biology · 2025Article
- Cell-to-cell translocation of florigen is inhibited by low ambient temperature through abscisic acid signaling inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Florigen-producing cells express FPF1-LIKE PROTEIN 1 to accelerate flowering and stem growth in Arabidopsis.Developmental cell · 2025Article
- Genome-Wide Identification and Phylogenetic Characterization of the FTIP Gene Family in Maize (Genes · 2025Article
82 more citing papers are in PubMed but not listed here.
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8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The capacity to respond to day length, photoperiodism, is crucial for flowering plants to adapt to seasonal change. The photoperiodic control of flowering in plants is mediated by a long-distance mobile floral stimulus called florigen that moves from leaves to the shoot apex. Although the proteins encoded by FLOWERING LOCUS T (FT) in Arabidopsis and its orthologs in other plants are identified as the long-sought florigen, whether their transport is a simple diffusion process or under regulation remains elusive. Here we show that an endoplasmic reticulum (ER) membrane protein, FT-INTERACTING PROTEIN 1 (FTIP1), is an essential regulator required for FT protein transport in Arabidopsis. Loss of function of FTIP1 exhibits late flowering under long days, which is partly due to the compromised FT movement to the shoot apex. FTIP1 and FT share similar mRNA expression patterns and subcellular localization, and they interact specifically in phloem companion cells. FTIP1 is required for FT export from companion cells to sieve elements, thus affecting FT transport through the phloem to the SAM. Our results provide a mechanistic understanding of florigen transport, demonstrating that FT moves in a regulated manner and that FTIP1 mediates FT transport to induce flowering.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.