Evidence map›Paper›PMID 22529222›Full record

SynthesisNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2013

Flavored and nonflavored smokeless tobacco products: rate, pattern of use, and effects.

Andrew J Oliver, Joni A Jensen, Rachel I Vogel, Amanda J Anderson, Dorothy K Hatsukami

Open access · bronzeAbstract readMeta-Analysis
In one paragraph

Synthesis in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Acute effects of snus in never-tobacco users: a pilot study.The American journal of drug and alcohol abuse · 2018
    Trial
  3. Article
  4. Use of Flavored and Modified Risk Smokeless Tobacco Products Among American Indian Adults.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Article
  5. A Method for Amending Loose Smokeless Tobacco With Menthol for Administration in Clinical Studies.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. 9. Flavours in novel and emerging nicotine and tobacco products.World Health Organization technical report series · 2021
    Article
  10. Article
  11. Correlates of youth vaping flavor preferences.Preventive medicine reports · 2020
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. The Effect of Tobacco Control Policies on US Smokeless Tobacco Use: A Structured Review.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Andrew J OliverTobacco Research Programs, Department of Psychiatry, University of Minnesota, Minneapolis, MN 55414, USA.
Joni A Jensen
Rachel I Vogel
Amanda J Anderson
Dorothy K Hatsukami
University of Minnesota · US

Funding

TOBACCO REDUCTION STRATEGIES FOR PATIENTS WITH CARDIAC DISEASEP50DA013333 · NIDA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI PENTEL, PAUL R · 1999 to 2008
$16.8M
Novel Determinants and Measures of Smokeless Tobacco UseR01CA141531 · NCI · UNIVERSITY OF MINNESOTA · PI HATSUKAMI, DOROTHY K · 2009 to 2014
$2.8M
Evaluation of Oral Tobacco as a Harm Reduction Method for SmokersR01CA135884 · NCI · UNIVERSITY OF MINNESOTA · PI HATSUKAMI, DOROTHY K · 2008 to 2013
$2.7M
Treatment of Smokeless Tobacco UsersR01DA014404 · NIDA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI HATSUKAMI, DOROTHY K · 2001 to 2008
$1.7M
NCI NIH HHS 5R01CA135884NCI NIH HHS P50CA13333NCI NIH HHS R01 CA135884NCI NIH HHS R01 CA141531NCI NIH HHS R01CA141531NIDA NIH HHS 5R01DA014404NIDA NIH HHS P50 DA013333NIDA NIH HHS R01 DA014404
6 · The paper itself

Abstract

introductionThe initiation and maintenance of tobacco use are influenced by several factors, but of equal and often overlooked importance, until recently, is the palatability of the product. Because of the role that flavor may play in the initiation and maintenance of tobacco use, the Food and Drug Administration has decided to ban the use of flavorings, other than menthol, from cigarettes. To date, little attention has been paid to the impact of flavoring in smokeless tobacco (ST) products.

methodsThis study combined the data from 5 previously completed treatment or switching studies to examine the choice of brand flavor in the course of ST use, from initiation to regular use.

resultsThe analyses revealed that a majority of subjects' first and current choice of product was flavored, specifically mint or wintergreen, and that a significant number of ST users switched to a flavored brand after already initiating ST use with a regular nonflavored product. In this population, however, flavored products did not appear to lead to greater dependence or increased exposure to nicotine or carcinogens.

conclusionsMore treatment seeking ST users began by using mint-flavored product and switched to and were current users of mint-flavored products. It is possible that mint products play a role in the initiation and maintenance of ST use.

Indexed as

Flavoring AgentsTobacco, SmokelessAdolescentAdultAgedHumansMenthaMiddle AgedYoung AdultFlavoring Agents

Identifiers

PMID22529222
PMCPMC3524058
OpenAlexW2167672244

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.