Evidence map›Paper›PMID 22528676›Full record

ReviewJournal of cardiovascular translational research2012

Cardiovascular disease risk in young people with type 1 diabetes.

Janet K Snell-Bergeon, Kristen Nadeau

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Journal of cardiovascular translational research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 68 citations in OpenAlex.

  1. Trial
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  5. Beyond HbAFrontiers in endocrinology · 2026
    Review
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  16. Bariatric surgery in patients with type 1 diabetes: special considerations are warranted.Therapeutic advances in endocrinology and metabolism · 2019
    Article
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4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Janet K Snell-BergeonBarbara Davis Center for Childhood Diabetes, University of Colorado Anschutz Medical Center, Aurora, CO 80045, USA. Janet.snell-bergeon@ucdenver.edu
Kristen Nadeau
University of Colorado Anschutz Medical Campus · US

Funding

ZOPOLRESTAT PHARMACOKINETICS IN DIABETICS WITH VARYING RENAL FUNCTIONM01RR000051 · NCRR · UNIVERSITY OF COLORADO DENVER · PI KOSMISKI, LISA A. · 1985 to 2008
$52.6M
Determinants of Accelerated CVD in Type 1 DiabetesR01HL079611 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI REWERS, MARIAN J. · 2004 to 2007
$2.3M
NCRR NIH HHS M01 RR000051NHLBI NIH HHS R01 HL079611NHLBI NIH HHS R01 HL61753NIDDK NIH HHS 1R56DK088971-01NIDDK NIH HHS P30 DK57516
6 · The paper itself

Abstract

Cardiovascular disease (CVD) is the most frequent cause of death in people with type 1 diabetes (T1D), despite modern advances in glycemic control and CVD risk factor modification. CVD risk identification is essential in this high-risk population, yet remains poorly understood. This review discusses the risk factors for CVD in young people with T1D, including hyperglycemia, traditional CVD risk factors (dyslipidemia, smoking, physical activity, hypertension), as well as novel risk factors such as insulin resistance, inflammation, and hypoglycemia. We present evidence that adverse changes in cardiovascular function, arterial compliance, and atherosclerosis are present even during adolescence in people with T1D, highlighting the need for earlier intervention. The methods for investigating cardiovascular risk are discussed and reviewed. Finally, we discuss the observational studies and clinical trials which have thus far attempted to elucidate the best targets for early intervention in order to reduce the burden of CVD in people with T1D.

Indexed as

AdolescentAdultAge FactorsBiomarkersBlood GlucoseCardiovascular DiseasesCardiovascular SystemChildDiabetes ComplicationsDiabetes Mellitus, Type 1Diabetic AngiopathiesEarly Medical InterventionFemaleHumansMalePredictive Value of TestsBiomarkersBlood Glucose

Identifiers

PMID22528676
OpenAlexW2033414691

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.