Evidence map›Paper›PMID 22528274›Full record

GuidelineNeurocritical care2012

Guidelines for the evaluation and management of status epilepticus.

Gretchen M Brophy, Rodney Bell, Jan Claassen, Brian Alldredge, Thomas P Bleck, Tracy Glauser, Suzette M Laroche, James J Riviello, Lori Shutter, Michael R Sperling and 3 more

Registry-linked trialAbstract readConsensus StatementPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Neurocritical care, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06564662 (Observational Single-Center Study), which is not on this map. Cited by 567 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
567citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06564662 recruitingnot on this mapstarted 2021, after this paper: background citation

Observational Single-Center Study: Improving Timely Detection of Electrographic Seizures by Use of Rapid-Response EEG in Children With Suspected Status Epilepticus Admitted to the Pediatric ICU

TypeobservationalSponsorChildren's Hospital at MontefioreRan2021 to 2026Enrolled60ConditionsStatus Epilepticus, ComaArmsRapid Response EEG
3 · Its place in the literature

Who cites it

567 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Singapore First Aid Guidelines 2026.Singapore medical journal · 2026
    Guideline
  2. Guideline
  3. Guideline
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
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  14. Article
  15. Perampanel as a candidate for polytherapy in Stage 1 Plus status epilepticus: biological rationale and translational limits.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

507 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Gretchen M BrophyDepartment of Pharmacotherapy & Outcomes Science, Virginia Commonwealth University, Medical College of Virginia Campus, 410 N. 12th Street, P.O. Box 980533, Richmond, VA 23298-0533, USA. gbrophy@vcu.edu
Rodney Bell
Jan Claassen
Brian Alldredge
Thomas P Bleck
Tracy Glauser
Suzette M Laroche
James J Riviello
Lori Shutter
Michael R Sperling
David M Treiman
Paul M Vespa
Neurocritical Care Society Status Epilepticus Guideline Writing Committee

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Status epilepticus (SE) treatment strategies vary substantially from one institution to another due to the lack of data to support one treatment over another. To provide guidance for the acute treatment of SE in critically ill patients, the Neurocritical Care Society organized a writing committee to evaluate the literature and develop an evidence-based and expert consensus practice guideline. Literature searches were conducted using PubMed and studies meeting the criteria established by the writing committee were evaluated. Recommendations were developed based on the literature using standardized assessment methods from the American Heart Association and Grading of Recommendations Assessment, Development, and Evaluation systems, as well as expert opinion when sufficient data were lacking.

Indexed as

AnticonvulsantsCritical CareEvidence-Based MedicineHumansStatus EpilepticusAnticonvulsants

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.