Evidence map›Paper›PMID 22527978›Full record

ReviewJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs2012

Bioactive polymer scaffold for fabrication of vascularized engineering tissue.

Irza Sukmana

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  16. Review
  17. Journal of Artificial Organs 2012: the year in review.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Irza SukmanaMedical Devices and Implant Technology (Mediteg) Research Group, Department of Biomechanics and Biomedical Materials, Universiti Teknologi Malaysia, Block P23 UTM Skudai, 81310 Johor Bahru, Johore, Malaysia. Irza.Sukmana@gmail.com

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue engineering seeks strategies to design polymeric scaffolds that allow high-cell-density cultures with signaling molecules and suitable vascular supply. One major obstacle in tissue engineering is the inability to create thick engineered-tissue constructs. A pre-vascularized tissue scaffold appears to be the most favorable approach to avoid nutrient and oxygen supply limitations as well as to allow waste removal, factors that are often hurdles in developing thick engineered tissues. Vascularization can be achieved using strategies in which cells are cultured in bioactive polymer scaffolds that can mimic extracellular matrix environments. This review addresses recent advances and future challenges in developing and using bioactive polymer scaffolds to promote tissue construct vascularization.

Indexed as

Tissue EngineeringTissue ScaffoldsEndothelial CellsExtracellular MatrixHumansNeovascularization, PhysiologicPolymersPolymers

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.