ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2012
Assessment of transient ischemic dilation (TID) ratio in gated SPECT myocardial perfusion imaging (MPI) using regadenoson, a new agent for pharmacologic stress testing.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- A Novel Quantitative Analysis in Myocardial Perfusion Imaging: How does it compare to the "Golden Eye"?Zeitschrift fur medizinische Physik · 2026Article
- Quality metrics for single-photon emission computed tomography myocardial perfusion imaging: an ASNC information statement.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Review
- Non-invasive Imaging in Patients With Chronic Total Occlusions of the Coronary Arteries-What Does the Interventionalist Need for Success?Frontiers in cardiovascular medicine · 2021Review
- How variable are the volumetric measurements from gated perfusion SPECT when a one-day stress-rest protocol is used?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Computer derived transient ischemic dilation ratio for identifying extensive coronary artery disease using a CZT camera and imaging in the upright position.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Normal limits for transient ischemic dilation withJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Review of cardiovascular imaging in the journal of nuclear cardiology in 2016: Part 2 of 2-myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Review
- Long-term prognostic implications of myocardial perfusion imaging in octogenarians: an all-comer, cohort study.European journal of nuclear medicine and molecular imaging · 2017Article
- Prognostic impact of TID in regadenoson MPI: Some patients and certain events.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- Prognostic value of transient ischemic dilation with regadenoson myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- The reproducibility and prognostic value of serial measurements of heart rate response to regadenoson during myocardial perfusion imaging.European journal of nuclear medicine and molecular imaging · 2016Article
- The prognostic value of non-perfusion variables obtained during vasodilator stress myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Review
- The significance of automatically measured transient ischemic dilation in identifying severe and extensive coronary artery disease in regadenoson, single-isotope technetium-99m myocardial perfusion SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Article
- Contemporary relevance of TID: Based on the company it keeps.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Article
- Assessing clinical impact of myocardial perfusion studies: ischemia or other prognostic indicators?Current cardiology reports · 2014Review
- B - Flow assessment of femoral artery as predictor of coronary artery disease in patients evaluated for chest pain by radionuclide myocardial perfusion scintigraphy.World journal of nuclear medicineArticle
- Transient Ischemic Dilation Ratio in Regadenoson, Single Isotope Gated Single-photon Emission Computed Tomography Myocardial Perfusion Imaging.World journal of nuclear medicineArticle
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Abstract
backgroundAbnormal values of the transient ischemic dilation (TID) ratio are associated with severe and extensive coronary artery disease (CAD). The objective of this study was to determine the relationship between TID, determined from stress and rest ventricular volumes during regadenoson gated single-photon emission computed tomography myocardial perfusion imaging (MPI) dual isotope studies, and the extent of CAD found during coronary angiography.
methods195 patients who underwent dual isotope MPI with regadenoson and cardiac angiography between March 2009 and February 2010 were analyzed. TID was calculated using commercially available software, Emory Cardiac Toolbox. Mean TID values were compared across disease types. A threshold for abnormal TID was determined by adding two standard deviations (SDs) to the mean TID of the "non-obstructive CAD" subgroup.
resultsIn the 195-patient group analyzed, the mean TID ratio for non-obstructive CAD (n = 104) was found to be 1.09 with a SD of 0.15. In a subgroup of patients whose angiogram was within 3 months of MPI (n = 155), the mean TIDs for non-obstructive disease (n = 81), single-vessel disease (n = 35), and multi-vessel disease (n = 39) were 1.09, 1.15, and 1.19 with SDs of 0.16, 0.19, and 0.26, respectively. Those with an abnormal TID had a crude and adjusted odds ratio of 3.4 for multi-vessel disease which was statistically significant. History of diabetes was not found to be a significant confounder, effect modifier, or mediator of the relationship between the TID and the vessel disease.
conclusionThe mean TID ratio in patients with multi-vessel disease was 1.19. The threshold for an abnormal TID was 1.39 with specificity of 95% and sensitivity of 15% for determining multi-vessel CAD status. We conclude that the level of TID in gated SPECT MPI using regadenoson is associated with the degree of CAD on angiography.
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