ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2012
Feasibility of myocardial perfusion imaging with half the radiation dose using ordered-subset expectation maximization with resolution recovery software.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Dose reduction in half-time myocardial perfusion SPECT-CT with multifocal collimation.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Trial
- Investigation of scatter energy window width and count levels for deep learning-based attenuation map estimation in cardiac SPECT/CT imaging.Physics in medicine and biology · 2024Article
- Simulating dose reduction for myocardial perfusion SPECT using a Poisson resampling method.Nuclear medicine and molecular imaging · 2021Article
- Impact of iterative reconstruction with resolution recovery in myocardial perfusion SPECT: phantom and clinical studies.Scientific reports · 2019Article
- Applying a correction factor to gated blood pool SPECT left ejection fraction value: Can this approach be used to get around a longstanding hurdle?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Personalized Models for Injected Activity Levels in SPECT Myocardial Perfusion Imaging.IEEE transactions on medical imaging · 2019Article
- Investigation of dose reduction in cardiac perfusion SPECT via optimization and choice of the image reconstruction strategy.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- The radiation dose to overweighted patients undergoing myocardial perfusion SPECT can be significantly reduced: validation of a linear weight-adjusted activity administration protocol.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Evaluation of general-purpose collimators against high-resolution collimators with resolution recovery with a view to reducing radiation dose in myocardial perfusion SPECT: A preliminary phantom study.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Effects of acquisition time and reconstruction algorithm on image quality, quantitative parameters, and clinical interpretation of myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013Article
- Angiographic correlation of myocardial perfusion imaging with half the radiation dose using ordered-subset expectation maximization with resolution recovery software.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013Article
- Recent advances in cardiac SPECT instrumentation and system design.Current cardiology reports · 2013Review
- Temporal evolution of administered activity in cardiac gated SPECT and patients' effective dose: analysis of an historical series.European journal of nuclear medicine and molecular imaging · 2013Article
- Feasibility of myocardial perfusion imaging with half the radiation dose in obese patients using ordered-subset expectation maximization with resolution recovery software.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013Article
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7 authors.
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Abstract
objectiveThis study sought to assess the feasibility of performing myocardial perfusion imaging (MPI) with half the technetium activity using ordered-subset expectation maximization with resolution recovery (OSEM-RR), an iterative reconstruction software developed to improve count statistics and acquisition time.
methodsTwo hundred eighteen patients referred for MPI were randomly allocated to undergo stress-rest or rest-stress protocols with standard full-dose (FD) injections of technetium (Tc)-99m sestamibi or half-dose (HD) injections and OSEM-RR processing. Dose activities were adjusted individually by weight. The groups were compared for image quality and clinical results.
resultsThe groups were similar for mean patient age, weight, and body mass index, sex distribution, pre-test probability of CAD and CAD prevalence. Mean Tc-99m activities for the low-dose and high-dose stages were as follows: FD group: 429 ± 85 MBq and 1132 ± 200 MBq; HD group: 263 ± 129 MBq and 629 ± 85 MBq (P < .0001 for both). Mean effective dose per study was 13.6 ± 1.4 mSv in the FD group and 7.7 ± 1.0 mSv in the HD group (P < .001). Over all image quality was good-to-excellent in 98% and 95% of the groups, respectively. However, when we analyzed the low-dose stage separately, image quality was slightly worse in the HD than the FD, though still within the good-to excellent range.
conclusionsMPI with nearly half the radiation dose is feasible with good image quality.
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