Evidence map›Paper›PMID 22527141›Full record

ArticleRheumatology international2013

Successful childbearing in two women with rheumatoid arthritis and a history of miscarriage after etanercept treatment.

Ikumi Natsumi, Yoshihiro Matsukawa, Kohji Miyagawa, Hitomi Kodaira, Toshitake Tanaka, Akira Horikoshi, Jin Takeuchi, Masami Takei, Mamoru Maejima, Jun Akimoto

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Rheumatology international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ikumi NatsumiDepartment of Internal Medicine, Nihon University Nerima-Hikarigaoka Hospital, Tokyo, Japan.
Yoshihiro Matsukawa
Kohji Miyagawa
Hitomi Kodaira
Toshitake Tanaka
Akira Horikoshi
Jin Takeuchi
Masami Takei
Mamoru Maejima
Jun Akimoto
Nihon University · JPWako University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two women with rheumatoid arthritis who had experienced miscarriages became pregnant while they were under etanercept treatment. One stopped etanercept after 3 weeks with increased doses of prednisolone, and the other restarted etanercept at a half doses 3 months later. They delivered a healthy baby at full term, and no problems in both expecting mothers and babies were observed. The use of etanercept in patients with rheumatoid arthritis seemed safe for pregnant mothers and their fetuses.

Indexed as

AdultAntirheumatic AgentsArthritis, RheumatoidEtanerceptFemaleHumansImmunoglobulin GInfant, NewbornPregnancyPregnancy ComplicationsReceptors, Tumor Necrosis FactorTumor Necrosis Factor-alphaAntirheumatic AgentsEtanerceptImmunoglobulin GReceptors, Tumor Necrosis FactorTumor Necrosis Factor-alpha

Identifiers

PMID22527141
OpenAlexW1985004287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.