ReviewApplied microbiology and biotechnology2012
Metabolic engineering of Rhizopus oryzae for the production of platform chemicals.
Review in Applied microbiology and biotechnology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Lactic acid fermentation using Rhizopus spp.: current insights and future prospects.Bioresources and bioprocessing · 2025Review
- Structure and Functionality of Fermented Faba Bean: Influence of Particle Size andFoods (Basel, Switzerland) · 2025Article
- Ecological factors that drive microbial communities in culturally diverse fermented foods.BMC microbiology · 2025Article
- Tuning fungal promoters for the expression of eukaryotic proteins.World journal of microbiology & biotechnology · 2024Review
- Studies on the Enzymatic Degradation Process of Epoxy-Polyurethane Compositions Obtained with Raw Materials of Natural Origin.Molecules (Basel, Switzerland) · 2024Article
- Application of microbial resources in biorefineries: Current trend and future prospects.Heliyon · 2024Review
- Microbial cell factories based on filamentous bacteria, yeasts, and fungi.Microbial cell factories · 2023Review
- Antagonistic Effect of Plant Growth-Promoting Fungi Against Fusarium Wilt Disease in Tomato: In vitro and In vivo Study.Applied biochemistry and biotechnology · 2022Article
- Production of Primary Metabolites byMolecules (Basel, Switzerland) · 2022Article
- Impact of Cellulolytic Fungi on Biodegradation of Hemp Shives and Corn Starch-Based Composites with Different Flame-Retardants.Microorganisms · 2022Article
- Transformation and CRISPR-Cas9-mediated homologous recombination in the fungusSTAR protocols · 2022Article
- Recent Molecular Tools for the Genetic Manipulation of Highly Industrially Important Mucoromycota Fungi.Journal of fungi (Basel, Switzerland) · 2021Review
- Restricted Nitrogen and Water Applications in the Orchard Modify the Carbohydrate and Amino Acid Composition of Nonpareil and Carmel Almond Hulls.Metabolites · 2021Article
- Biosynthesis pathways and strategies for improving 3-hydroxypropionic acid production in bacteria.World journal of microbiology & biotechnology · 2021Review
- Article
- Comparative proteomic analysis of3 Biotech · 2020Article
- Lactic acid production - producing microorganisms and substrates sources-state of art.Heliyon · 2020Review
- The CRISPR toolbox in medical mycology: State of the art and perspectives.PLoS pathogens · 2020Review
- Valorization of cheese whey and orange molasses for fungal biomass production by submerged fermentation with Rhizopus sp.Bioprocess and biosystems engineering · 2019Article
- Fumaric acid production using renewable resources from biodiesel and cane sugar production processes.Environmental science and pollution research international · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rhizopus oryzae is a filamentous fungus belonging to the Zygomycetes. It is among others known for its ability to produce the sustainable platform chemicals L: -(+)-lactic acid, fumaric acid, and ethanol. During glycolysis, all fermentable carbon sources are metabolized to pyruvate and subsequently distributed over the pathways leading to the formation of these products. These platform chemicals are produced in high yields on a wide range of carbon sources. The yields are in excess of 85 % of the theoretical yield for L: -(+)-lactic acid and ethanol and over 65 % for fumaric acid. The study and optimization of the metabolic pathways involved in the production of these compounds requires well-developed metabolic engineering tools and knowledge of the genetic makeup of this organism. This review focuses on the current metabolic engineering techniques available for R. oryzae and their application on the metabolic pathways of the main fermentation products.
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