Evidence map›Paper›PMID 22526568›Full record

ArticleCurrent microbiology2012

Quantification of subgingival bacterial pathogens at different stages of periodontal diseases.

Heon-Jin Lee, Jin-Kyoung Kim, Je-Yeol Cho, Jae-Mok Lee, Su-Hyung Hong

Abstract read
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In one paragraph

Article in Current microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

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  9. The Clinical Importance ofFrontiers in cellular and infection microbiology · 2018
    Review
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  11. Global Epidemiology of Campylobacter Infection.Clinical microbiology reviews · 2015
    Review
  12. Article
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  14. Antibacterial Activity of Myristica fragrans against Oral Pathogens.Evidence-based complementary and alternative medicine : eCAM · 2012
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Heon-Jin LeeDepartment of Oral Microbiology, School of Dentistry, Kyungpook National University, 2-188-1 Samduk-dong, Jung-gu, Daegu, South Korea.
Jin-Kyoung Kim
Je-Yeol Cho
Jae-Mok Lee
Su-Hyung Hong
Kyungpook National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anaerobic gram-negative oral bacteria such as Treponema denticola, Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Campylobacter rectus, and Fusobacterium nucleatum are closely associated with periodontal diseases. We measured the relative population (bacterial levels) of these oral pathogens in subgingival tissues of patients at different stages of Korean chronic periodontal diseases. We divided the individuals into those with chronic gingivitis (G), moderate periodontitis (P1), severe periodontitis (P2), and normal individuals (N) (n = 20 for each group) and subgingival tissue samples were collected. We used real-time PCR with TaqMan probes to evaluate the change of periodontal pathogens among different stages of periodontitis. Bacterial levels of A. actinomycetemcomitans and C. rectus are significantly increased in individuals with chronic gingivitis and moderate periodontitis, but unchanged in severe periodontitis patients. These results suggest that analyzing certain bacterial levels among total oral pathogens may facilitate understanding of the role of periodontal bacteria in the early stages of periodontitis.

Indexed as

AdultBacteriaChronic DiseaseDisease ProgressionDNA, BacterialFemaleHumansMaleMiddle AgedPeriodontal DiseasesRepublic of KoreaRNA, Ribosomal, 16SDNA, BacterialRNA, Ribosomal, 16S

Identifiers

PMID22526568
OpenAlexW2042539157

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.