Evidence map›Paper›PMID 22526475›Full record

ArticleClinical rheumatology2012

Normal QT dispersion in colchicine-resistant familial Mediterranean fever (FMF).

Udi Nussinovitch, Avi Livneh, Benjamin Volovitz, Moshe Nussinovitch, Ilan Ben-Zvi, Merav Lidar, Naomi Nussinovitch

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Cardiac disease in familial Mediterranean fever.Rheumatology international · 2018
    Review
  6. Article
  7. Article
  8. Article
  9. Familial Mediterranean fever: An updated review.European journal of rheumatology · 2014
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Udi NussinovitchIsrael Naval Medical Institute, IDF Medical Corps, Haifa, Israel.
Avi Livneh
Benjamin Volovitz
Moshe Nussinovitch
Ilan Ben-Zvi
Merav Lidar
Naomi Nussinovitch
Sheba Medical Center · ILTel Aviv University · ILHaifa Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association between familial Mediterranean fever (FMF) and subclinical cardiac disease remains controversial. The aim of the current study was to evaluate whether FMF patients, who do not respond to colchicine treatment, and thereby endure persistent inflammation, have increased QT dispersion (QTd) values. Twenty-two FMF patients and 22 age- and sex-matched control subjects were included in the study. Repolarization and QT dispersion parameters were computed from 12-lead ECG recording using designated computer software, and results of five beats were subsequently averaged. Both FMF patients and controls had similar comorbidities, similar values of average QT, average corrected QT interval length, average QTd interval, average QT corrected dispersion, QT dispersion ratio, JT dispersion (JTd), and JT corrected dispersion. In conclusion, FMF patients who were unresponsive to colchicine treatment and did not develop amyloidosis had normal QTd and JTd parameters, indicating a non-increased risk for repolarization-associated ventricular arrhythmias.

Indexed as

AdultArrhythmias, CardiacCase-Control StudiesColchicineDrug ResistanceElectrocardiographyFamilial Mediterranean FeverFemaleHeart Conduction SystemHumansMaleMiddle AgedColchicine

Identifiers

PMID22526475
OpenAlexW2011659912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.