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ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2012

Comparison between Acuros XB and Brainlab Monte Carlo algorithms for photon dose calculation.

M Mißlbeck, P Kneschaurek

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Hounsfield units variations: impact on CT-density based conversion tables and their effects on dose distribution.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2014
    Article
4 · The record

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5 · Who and what money

Authors and funding

2 authors.

M MißlbeckKlinik und Poliklinik für Strahlentherapie und Radiologische Onkologie, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany. Misslbeck@lrz.tu-muenchen.de
P Kneschaurek

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe Acuros® XB dose calculation algorithm by Varian and the Monte Carlo algorithm XVMC by Brainlab were compared with each other and with the well-established AAA algorithm, which is also from Varian.

methodsFirst, square fields to two different artificial phantoms were applied: (1) a "slab phantom" with a 3 cm water layer, followed by a 2 cm bone layer, a 7 cm lung layer, and another 18 cm water layer and (2) a "lung phantom" with water surrounding an eccentric lung block. For the slab phantom, depth-dose curves along central beam axis were compared. The lung phantom was used to compare profiles at depths of 6 and 14 cm. As clinical cases, the CTs of three different patients were used. The original AAA plans with all three algorithms using open fields were recalculated.

resultsThere were only minor differences between Acuros and XVMC in all artificial phantom depth doses and profiles; however, this was different for AAA, which had deviations of up to 13% in depth dose and a few percent for profiles in the lung phantom. These deviations did not translate into the clinical cases, where the dose-volume histograms of all algorithms were close to each other for open fields.

conclusionOnly within artificial phantoms with clearly separated layers of simulated tissue does AAA show differences at layer boundaries compared to XVMC or Acuros. In real patient CTs, these differences in the dose-volume histogram of the planning target volume were not observed.

Indexed as

AlgorithmsMonte Carlo MethodSoftwareHumansPhotonsRadiometryRadiotherapy, Computer-AssistedRadiotherapy DosageRadiotherapy Planning, Computer-AssistedReproducibility of ResultsSensitivity and SpecificitySoftware Validation

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