ArticleObstetrics and gynecology2012
Antenatal steroids for treatment of fetal lung immaturity after 34 weeks of gestation: an evaluation of neonatal outcomes.
Article in Obstetrics and gynecology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: immunomodulatory anti-rheumatic drugs and corticosteroids.Rheumatology (Oxford, England) · 2023Guideline
- Prevalence of respiratory distress syndrome among late preterm infants admitted to a neonatal intensive care unit in Saudi Arabia: A retrospective study.Saudi medical journal · 2025Article
- Article
- The role of antenatal corticosteroids in twin pregnancy.Frontiers in pharmacology · 2023Review
- Late preterm antenatal corticosteroids in singleton and twin gestations: a retrospective cohort study.BMC pregnancy and childbirth · 2022Article
- Neonatal hypoglycemia after initiation of late preterm antenatal corticosteroids.Journal of perinatology : official journal of the California Perinatal Association · 2020Article
- Article
- Dexamethasone-induced Intra-Uterine Growth Restriction impacts NOSTRIN and its downstream effector genes in the rat mesometrial uterus.Scientific reports · 2018Article
- Prediction of neonatal respiratory morbidity by quantitative ultrasound lung texture analysis: a multicenter study.American journal of obstetrics and gynecology · 2017Article
- Antenatal Corticosteroid Administration for Reducing the Risk of Neonatal Morbidities from Prematurity.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2016Article
- Antenatal steroids: can we optimize the dose?Current opinion in obstetrics & gynecology · 2014Review
- Late preterm births: a retrospective analysis of the morbidity risk stratified for gestational age.SpringerPlus · 2014Article
- Metabolic and hormonal effects of antenatal betamethasone after 35 weeks of gestation.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAGArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo estimate whether antenatal corticosteroids given after fetal lung immaturity in pregnancies at 34 weeks of gestation or more would improve neonatal outcomes and, in particular, respiratory outcomes.
methodsWe compared outcomes of 362 neonates born at 34 weeks of gestation or more after fetal lung maturity testing: 102 with immature fetal lung indices were treated with antenatal corticosteroids followed by planned delivery within 1 week; 76 with immature fetal lung indices were managed expectantly; and 184 were delivered after mature amniocentesis. Primary outcomes were composites of neonatal and respiratory morbidity.
resultsCompared with corticosteroid-exposed neonates those born after mature amniocentesis had lower rates of adverse neonatal (26.5% compared with 14.1%, adjusted odds ratio [OR] 0.51, 95% confidence interval [CI] 0.27-0.96) and adverse respiratory outcomes (9.8% compared with 3.3%, adjusted OR 0.33, 95% CI 0.11-0.98); newborns born after expectant management had significantly less respiratory morbidity (1.3% compared with 9.8%, adjusted OR 0.11, 95% CI 0.01-0.92) compared with corticosteroid-exposed newborns.
conclusionAdministration of antenatal corticosteroids after immature fetal lung indices did not reduce respiratory morbidity in neonates born at 34 weeks of gestation or more. Our study supports prolonging gestation until delivery is otherwise indicated. LEVEL OF EVIDENCE: II.
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