Evidence map›Paper›PMID 22525604›Full record

SynthesisOral oncology2012

A systematic review of head and neck cancer quality of life assessment instruments.

Bukola Ojo, Eric M Genden, Marita S Teng, Kathrin Milbury, Krzysztof J Misiukiewicz, Hoda Badr

Abstract readSystematic Review
In one paragraph

Synthesis in Oral oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 10 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 10 syntheses or guidelines pooled it, 185 citations in OpenAlex.

  1. Pooled it
  2. Functional and quality-of-life outcomes following salvage surgery for recurrent squamous cell carcinoma of the head and neck: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Pooled it
  3. A systematic review of body image measures for people diagnosed with head and neck cancer (HNC).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
    Pooled it
  4. A systematic review of psychological interventions for patients with head and neck cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
    Pooled it
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  9. Guideline
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  13. Confounding factors associated with oral mucositis assessment in patients receiving chemoradiotherapy for head and neck cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017
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  18. Assessing Long-Term Quality of Life Concerns Through Survivorship Clinic in Head and Neck Cancer Patients.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Article
  19. Subjective and objective effects of radioiodine therapy on the sense of smell.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  20. Review

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bukola OjoDepartment of Oncological Sciences, Mount Sinai School of Medicine, New York, NY, USA. Electronic address: Bukola.Ojo@mssm.edu.
Eric M GendenDepartment of Otolaryngology-Head and Neck Surgery, Mount Sinai School of Medicine, New York, NY, USA.
Marita S TengDepartment of Otolaryngology-Head and Neck Surgery, Mount Sinai School of Medicine, New York, NY, USA.
Kathrin MilburyDepartment of Behavioral Science, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
Krzysztof J MisiukiewiczDepartment of Otolaryngology-Head and Neck Surgery, Mount Sinai School of Medicine, New York, NY, USA; Department of Medicine, Hematology and Medical Oncology, Mount Sinai School of Medicine, New York, NY, USA.
Hoda BadrDepartment of Oncological Sciences, Mount Sinai School of Medicine, New York, NY, USA.
Icahn School of Medicine at Mount Sinai · USThe University of Texas MD Anderson Cancer Center · US

Funding

Spousal Support, Emotional Disclosure, and Adjustment to Head and Neck CancerK07CA124668 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BADR, HODA J. · 2008 to 2012
$779k
Couple-Based Mind-Body Program for Lung Cancer Patients and their PartnersK01AT007559 · NCCIH · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MILBURY, KATHRIN · 2013 to 2017
$652k
NCCIH NIH HHS K01 AT007559NCI NIH HHS K07 CA124668NCI NIH HHS K07CA124668
6 · The paper itself

Abstract

Although quality of life (QOL) is an important treatment outcome in head and neck cancer (HNC), cross-study comparisons have been hampered by the heterogeneity of measures used and the fact that reviews of HNC QOL instruments have not been comprehensive to date. We performed a systematic review of the published literature on HNC QOL instruments from 1990 to 2010, categorized, and reviewed the properties of the instruments using international guidelines as reference. Of the 2766 articles retrieved, 710 met the inclusion criteria and used 57 different head and neck-specific instruments to assess QOL. A review of the properties of these utilized measures and identification of areas in need of further research is presented. Given the volume and heterogeneity of QOL measures, there is no gold standard questionnaire. Therefore, when selecting instruments, researchers should consider not only psychometric properties but also research objectives, study design, and the pitfalls and benefits of combining different measures. Although great strides have been made in the assessment of QOL in HNC and researchers now have a plethora of quality instruments to choose from, more work is needed to improve the clinical utility of these measures in order to link QOL research to clinical practice. This review provides a platform for head and neck-specific instrument comparisons, with suggestions of important factors to consider in the systematic selection of QOL instruments, and is a first step towards translation of QOL assessment into the clinical scene.

Indexed as

Head and Neck NeoplasmsHumansPsychometricsQuality of LifeRetrospective StudiesSurveys and QuestionnairesTreatment Outcome

Identifiers

PMID22525604
PMCPMC3406264
OpenAlexW2013526284

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.