BRCA1 and BRCA2: a common pathway of genome protection but different breast cancer subtypes.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed.

1. Heterogeneity of estrogen receptor expression in circulating tumor cells from metastatic breast cancer patients.PloS one · 2013
   Trial
2. Unveiling pathogenic mutations in BRCA1 and BRCA2 genes across head and neck squamous cell carcinoma patients via next generation sequencing.American journal of cancer research · 2023
   Article
3. Understanding and predicting the functional consequences of missense mutations in BRCA1 and BRCA2.Scientific reports · 2022
   Article
4. Breast Cancer; Discovery of Novel Diagnostic Biomarkers, Drug Resistance, and Therapeutic Implications.Frontiers in molecular biosciences · 2022
   Review
5. Germline RAD51B variants confer susceptibility to breast and ovarian cancers deficient in homologous recombination.NPJ breast cancer · 2021
   Article
6. Spatiotemporal strategies to identify aggressive biology in precancerous breast biopsies.WIREs mechanisms of disease · 2021
   Review
7. An information-theoretical analysis of gene nucleotide sequence structuredness for a selection of aging and cancer-related genes.Genomics & informatics · 2020
   Article
8. An immune-centric exploration of BRCA1 and BRCA2 germline mutation related breast and ovarian cancers.BMC cancer · 2020
   Article
9. Reviewing the characteristics of BRCA and PALB2-related cancers in the precision medicine era.Genetics and molecular biology · 2019
   Article
10. A portable BRCA1-HAC (human artificial chromosome) module for analysis of BRCA1 tumor suppressor function.Nucleic acids research · 2014
    Article
11. JMJD1C demethylates MDC1 to regulate the RNF8 and BRCA1-mediated chromatin response to DNA breaks.Nature structural & molecular biology · 2013
    Article

Corrections and comments

• Comment on
  BRCA1 and BRCA2: different roles in a common pathway of genome protection.2011

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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