Evidence map›Paper›PMID 22525324›Full record

ArticleThe journal of spinal cord medicine2012

A report of anticipated benefits of functional electrical stimulation after spinal cord injury.

Ashraf S Gorgey, Christopher R Harnish, Jonathan A Daniels, David R Dolbow, Allison Keeley, Jewel Moore, David R Gater

2 registry-linked trialsOpen access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of spinal cord medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03810963 nacompletednot on this mapstarted 2017, after this paper: background citation

Electrically Induced Cycling and Nutritional Counseling for Counteracting Obesity After SCI

TypeinterventionalSponsorWilliam Carey UniversityRan2017 to 2019Enrolled15ConditionsSpinal Cord InjuriesArmsHIIT-FES Cycling combined with Nutritional Counseling, Nutritional Counseling Only
NCT05187650 narecruitingnot on this mapstarted 2022, after this paper: background citation

Effectiveness of a Powered Exoskeleton Combined With Functional Electric Stimulation for Patients With Chronic Spinal Cord Injury: a Randomized Controlled Trial

TypeinterventionalSponsorMario WidmerRan2022 to 2027Enrolled34ConditionsSpinal Cord Injuries, Gait Disorders, NeurologicArmsEkso (EksoNR, Ekso Bionics), FES (RehaMove2, Hasomed)
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ashraf S GorgeyHunter Holmes McGuire Veterans Affairs Medical Center, Richmond, VA 23249, USA. ashraf.gorgey@va.gov
Christopher R Harnish
Jonathan A Daniels
David R Dolbow
Allison Keeley
Jewel Moore
David R Gater
Hunter Holmes McGuire VA Medical Center · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR031990 · NCRR · VIRGINIA COMMONWEALTH UNIVERSITY · PI CLORE, JOHN N. · 2010 to 2011
$7.7M
NCRR NIH HHS UL1 RR031990NCRR NIH HHS UL1RR031990
6 · The paper itself

Abstract

backgroundFunctional electrical stimulation (FES) has been regularly used to offset several negative body composition and metabolic adaptations following spinal cord injury (SCI). However, the outcomes of many FES trials appear to be controversial and incoherent.

objectiveTo document the potential consequences of several factors (e.g. pain, spasms, stress and lack of dietary control) that may have attenuated the effects on body composition and metabolic profile despite participation in 21 weeks of FES training. PARTICIPANT: A 29-year-old man with T6 complete SCI participated in 21 weeks of FES, 4 days per week.

methodsPrior to and following training, the participant performed arm-crank-graded exercise testing to measure peak VO(2). Tests conducted included anthropometrics and dual energy X-ray absorptiometry body composition assessments, resting energy expenditure, plasma lipid profiles and intravenous glucose tolerance tests.

resultsThe participant frequently reported increasing pain, stress and poor eating habits. VO(2) peak decreased by 2.4 ml/kg/minute, body mass increased by 8.5 kg, and body mass index increased from 25 to 28 kg/m(2). Waist and abdominal circumferences increased by 2-4 cm, while %fat mass increased by 5.5%. Absolute increases in fat mass and fat-free mass of 8.4 and 1 kg, respectively, were reported. Fasting and peak plasma glucose increased by 12 and 14.5%, while lipid panel profiles were negatively impacted.

conclusionFailure to control for the listed negative emerging factors may obscure the expected body composition and metabolic profile adaptations anticipated from FES training.

Indexed as

Absorptiometry, PhotonAdultAmino AcidsBody CompositionBody Mass IndexChromiumElectric Stimulation TherapyEnergy MetabolismExercise TherapyHumansMaleMetabolomeNicotinic AcidsSpinal Cord InjuriesAmino AcidsChromiumglucose tolerance factorNicotinic Acids

Identifiers

PMID22525324
PMCPMC3304554
OpenAlexW2036160179

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.