Evidence map›Paper›PMID 22525225›Full record

ReviewSeminars in cell & developmental biology2012

Hippo signalling in the G2/M cell cycle phase: lessons learned from the yeast MEN and SIN pathways.

Alexander Hergovich, Brian A Hemmings

Abstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 87 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Localization and function of septins are susceptible to epitope tagging.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Review
  7. Membrane and organelle rearrangement during ascospore formation in budding yeast.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  8. Review
  9. Prognostic and Immunological Role ofInternational journal of molecular sciences · 2022
    Article
  10. Anterior-posterior pattern formation in ciliates.The Journal of eukaryotic microbiology · 2022
    Review
  11. Article
  12. Article
  13. Moonlighting at the Poles: Non-Canonical Functions of Centrosomes.Frontiers in cell and developmental biology · 2022
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Alexander HergovichUCL Cancer Institute, University College London, London, United Kingdom. a.hergovich@ucl.ac.uk
Brian A Hemmings
CRUK Lung Cancer Centre of Excellence · GBFriedrich Miescher Institute · CH

Funding

Wellcome Trust 090090Wellcome Trust 090090/Z/09/Z
6 · The paper itself

Abstract

Over the past decade Hippo kinase signalling has been established as an essential tumour suppressor pathway controlling tissue growth in flies and mammals. All members of the Hippo core signalling cassette are conserved from yeast to humans, whereby the yeast analogues of Hippo, Mats and Lats are central components of the mitotic exit network and septation initiation network in budding and fission yeast, respectively. Here, we discuss how far core Hippo signalling components in Drosophila melanogaster and mammals have reported similar mitotic functions as already established for their highly conserved yeast counterparts.

Indexed as

Cell DivisionG2 PhaseSignal TransductionAnimalsHumansProtein Serine-Threonine KinasesRNA Polymerase IIITranscriptional Elongation FactorsYeastsProtein Serine-Threonine KinasesRNA Polymerase IIITranscriptional Elongation Factors

Identifiers

PMID22525225
PMCPMC3459816
OpenAlexW2056411182

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.