Evidence map›Paper›PMID 22525009›Full record

Trial reportJournal of alternative and complementary medicine (New York, N.Y.)2012

Yoga breathing for cancer chemotherapy-associated symptoms and quality of life: results of a pilot randomized controlled trial.

Anand Dhruva, Christine Miaskowski, Donald Abrams, Michael Acree, Bruce Cooper, Steffanie Goodman, Frederick M Hecht

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of alternative and complementary medicine (New York, N.Y.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 61 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06263283 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Impact of an Educational Physiotherapy-Yoga Intervention on Perceived Stress in Women Treated With Brachytherapy for Cervical Cancer: a Randomized Controlled Trial

TypeinterventionalSponsorInstitut du Cancer de Montpellier - Val d'AurelleRan2024 to 2026Enrolled98ConditionsCervical Cancer, BrachytherapyArmssession of Kine-Yoga
NCT07312942 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effects of Adding a Controlled Breathing Protocol to a Therapeutic Exercise Program in Adults With Multiple Myeloma

TypeinterventionalSponsorUniversidad Complutense de MadridRan2026 to 2026Enrolled32ConditionsMultiple Myeloma, Breathing Techniques, Breathing Exercises, Exercise ActivityArmsControlled breathing exercise protocol + therapeutic exercise + initial education session, Therapeutic exercise + initial education session
3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 8 syntheses or guidelines pooled it.

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  13. Qualitative similarities and distinctions between participants' experiences with a yoga intervention and an attention control.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anand DhruvaOsher Center for Integrative Medicine, University of California, San Francisco, San Francisco, CA 94143, USA. anand.dhruva@ucsf.edu
Christine Miaskowski
Donald Abrams
Michael Acree
Bruce Cooper
Steffanie Goodman
Frederick M Hecht

Funding

A Whole Systems Approach to the Study of Ayurveda for Cancer SurvivorshipK23AT005340 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DHRUVA, ANAND · 2009 to 2013
$635k
NCCIH NIH HHS K23 AT005340-01
6 · The paper itself

Abstract

backgroundMany debilitating symptoms arise from cancer and its treatment that are often unrelieved by established methods. Pranayama, a series of yogic breathing techniques, may improve cancer-related symptoms and quality of life, but it has not been studied for this purpose.

objectivesA pilot study was performed to evaluate feasibility and to test the effects of pranayama on cancer-associated symptoms and quality of life.

designThis was a randomized controlled clinical trial comparing pranayama to usual care.

settingThe study was conducted at a university medical center. SUBJECTS: Patients receiving cancer chemotherapy were randomized to receive pranayama immediately or after a waiting period (control group).

interventionsThe pranayama intervention consisted of four breathing techniques taught in weekly classes and practiced at home. The treatment group received pranayama during two consecutive cycles of chemotherapy. The control group received usual care during their first cycle, and received pranayama during their second cycle of chemotherapy. OUTCOME MEASURES: Feasibility, cancer-associated symptoms (fatigue, sleep disturbance, anxiety, depression, stress), and quality of life were the outcomes.

resultsClass attendance was nearly 100% in both groups. Sixteen (16) participants were included in the final intent-to-treat analyses. The repeated-measures analyses demonstrated that any increase in pranayama dose, with dose measured in the number of hours practiced in class or at home, resulted in improved symptom and quality-of-life scores. Several of these associations--sleep disturbance (p=0.04), anxiety (p=0.04), and mental quality of life (p=0.05)--reached or approached statistical significance.

conclusionsYoga breathing was a feasible intervention among patients with cancer receiving chemotherapy. Pranayama may improve sleep disturbance, anxiety, and mental quality of life. A dose-response relationship was found between pranayama use and improvements in chemotherapy-associated symptoms and quality of life. These findings need to be confirmed in a larger study.

Indexed as

Breathing ExercisesMeditationQuality of LifeRespirationYogaAdultAgedAntineoplastic AgentsAnxietyDepressionEvaluation Studies as TopicFatigueFemaleHumansIntention to Treat AnalysisMaleAntineoplastic Agents

Identifiers

PMID22525009
PMCPMC3353818

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.