Trial reportJournal of cognitive neuroscience2012
Inducing negative affect increases the reward value of appetizing foods in dieters.
Trial report in Journal of cognitive neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 34 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Relation of Genetic Factors, Food Cues, and Self-Regulation With Excess Consumption and Adiposity in Children
Media Multi-tasking and Cued Overeating: Assessing the Pathway and Piloting an Intervention Using an Attentional Network Framework
Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 94 citations in OpenAlex.
- The influence of stress on the neural underpinnings of disinhibited eating: a systematic review and future directions for research.Reviews in endocrine & metabolic disorders · 2023Pooled it
- The role of incidental affective states in appetitive risk behavior: A meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2020Pooled it
- Food cue reactivity and craving predict eating and weight gain: a meta-analytic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2016Pooled it
- Trial
- Two facets of stress and indirect effects on child diet through emotion-driven eating.Eating behaviors · 2015Trial
- Emotional Eating Under Negative Affect: A Narrative Review from the Perspectives of Emotion Regulation and Reward Processes in Food Choice.Nutrients · 2026Review
- Bed nucleus of the stria terminalis connectivity during food cue and taste processing under stress.Nature communications · 2026Article
- Impact of bariatric surgery and predictive factors for eating disorders before and after surgery: a prospective observational study.Journal of eating disorders · 2026Article
- Adolescent Neural Reactivity to Alcohol Cues: The Role of Violence Exposure and Coping Motives.Behavioral sciences (Basel, Switzerland) · 2026Article
- Attentional biases in self-control are associated with reward cue-related brain activity.Social cognitive and affective neuroscience · 2026Article
- Testing a Reward-Processing Model of Negative Urgency in Women With and Without Binge Eating.Clinical psychological science : a journal of the Association for Psychological Science · 2025Article
- Exploring relationships among appetitive traits, negative affect, and binge eating in adults with overweight or obesity.Eating behaviors · 2024Article
- Contextualizing the Neural Vulnerabilities Model of Obesity.Nutrients · 2023Review
- The association between anxiety sensitivity and food cravings among individuals seeking treatment for weight-related behaviors.Eating behaviors · 2023Article
- The role of emotion in eating behavior and decisions.Frontiers in psychology · 2023Review
- Differential neural reward reactivity in response to food advertising medium in children.Frontiers in neuroscience · 2023Article
- Brain Responses to High-Calorie Visual Food Cues in Individuals with Normal-Weight or Obesity: An Activation Likelihood Estimation Meta-Analysis.Brain sciences · 2021Review
- Contributing roles of depression, anxiety, and impulsivity dimensions in eating behaviors styles in surgery candidates.Journal of eating disorders · 2021Article
- Effects of Appetitive and Aversive Motivational States on Wanting and Liking of Interpersonal Touch.Neuroscience · 2021Article
- The Neurobiology of Binge-eating Disorder Compared with Obesity: Implications for Differential Therapeutics.Clinical therapeutics · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Experiencing negative affect frequently precedes lapses in self-control for dieters, smokers, and drug addicts. Laboratory research has similarly shown that inducing negative emotional distress increases the consumption of food or drugs. One hypothesis for this finding is that emotional distress sensitizes the brain's reward system to appetitive stimuli. Using functional neuroimaging, we demonstrate that inducing negative affect in chronic dieters increases activity in brain regions representing the reward value of appetitive stimuli when viewing appetizing food cues. Thirty female chronic dieters were randomly assigned to receive either a negative (n = 15) or neutral mood induction (n = 15) immediately followed by exposure to images of appetizing foods and natural scenes during fMRI. Compared with chronic dieters in a neutral mood, those receiving a negative mood induction showed increased activity in the OFC to appetizing food images. In addition, activity to food images in the OFC and ventral striatum was correlated with individual differences in the degree to which the negative mood induction decreased participants' self-esteem. These findings suggest that distress sensitizes the brain's reward system to appetitive cues, thereby offering a mechanism for the oft-observed relationship between negative affect and disinhibited eating.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.