ArticleSpermatogenesis2011
The roles of the DAZ family in spermatogenesis: More than just translation?
Article in Spermatogenesis, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 76 citations in OpenAlex.
- BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Spaceflight multi-omics reveals vulnerabilities of human germ cell development.Science advances · 2026Article
- Y-CpG-based semen age prediction: analysis of vasectomized samples and development of an optimized multiplex assay evaluated in independent and mixed samples.International journal of legal medicine · 2026Article
- BOLL-Containing Aggregates Mediate the Translational Regulation During Human Oogenesis.Cell proliferation · 2026Article
- Article
- Loss of full-length DAZL isoform disrupts PABPC1-dependent translational regulation and meiosis.Cell death & disease · 2025Article
- Investigating the Impact of Bismuth Oxide Nanoparticles on Dazl Gene Expression and Spermatogenesis Indices in Male Mice.Biological trace element research · 2025Article
- Rapid detection of mouse spermatogenic defects by testicular cellular composition analysis via enhanced deep learning model.Andrology · 2025Article
- 3D Bioprinted Coaxial Testis Model Using Human Induced Pluripotent Stem Cells:A Step Toward Bicompartmental Cytoarchitecture and Functionalization.Advanced healthcare materials · 2025Article
- Identification of RNA Targets of Highly Conserved RNA Binding Proteins Essential for Animal Sperm Development.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Cloning, expression analysis and localization ofAnimal biotechnology · 2023Article
- Article
- RNA binding protein BOULE forms aggregates in mammalian testis.Journal of biomedical research · 2022Article
- Review
- RNA-binding protein Maca is crucial for gigantic male fertility factor gene expression, spermatogenesis, and male fertility, in Drosophila.PLoS genetics · 2021Article
- Article
- Expression of DAZL Gene in Selected Tissues and Association of Its Polymorphisms with Testicular Size in Hu Sheep.Animals : an open access journal from MDPI · 2020Article
- The ectopic expression of meiCT genes promotes meiomitosis and may facilitate carcinogenesis.Cell cycle (Georgetown, Tex.) · 2020Review
- Mitochondria Associated Germinal Structures in Spermatogenesis: piRNA Pathway Regulation and Beyond.Cells · 2020Review
- Dosage regulation, and variation in gene expression and copy number of human Y chromosome ampliconic genes.PLoS genetics · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The DAZ family of genes are important fertility factors in animals, including humans. The family consists of Y-linked DAZ, and autosomal homologs Boule and Dazl. All three genes encode RNA-binding proteins that are nearly exclusively expressed in germ cells. The DAZ family is highly conserved, with ancestral Boule present in sea anemones through humans, Dazl conserved among vertebrates, and DAZ present only in higher primates. Here we review studies on DAZ family genes from multiple organisms, and summarize the common features of each DAZ gene and their roles during spermatogenesis in animals. DAZ family proteins are thought to activate the translation of RNA targets, but recent work has uncovered additional functions. Boule, Dazl, and DAZ likely function through similar mechanisms, and we present known functions of the DAZ family in spermatogenesis, and discuss possible mechanisms in addition to translation activation.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.