Evidence map›Paper›PMID 22522323›Full record

ReviewAntiviral research2012

Alphaviruses: population genetics and determinants of emergence.

Scott C Weaver, Richard Winegar, Ian D Manger, Naomi L Forrester

Abstract readReview
In one paragraph

Review in Antiviral research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers.

0numbers the graph read from it
0cells of the map it votes in
106citing papers in PubMed
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

106 citing papers in PubMed, 209 citations in OpenAlex.

  1. Article
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  4. Review
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  14. Review
  15. Article
  16. Current perspectives on alphavirus encapsidation, assembly and budding.Frontiers in cellular and infection microbiology · 2025
    Review
  17. Article
  18. Review
  19. Article
  20. Article

46 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Scott C WeaverInstitute for Human Infections and Immunity and Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA. sweaver@utmb.edu
Richard Winegar
Ian D Manger
Naomi L Forrester
The University of Texas Medical Branch at Galveston · USMenlo School · USSRI International · US

Funding

WRCE Nonhuman Primate CoreU54AI057156 · NIAID · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI WALKER, DAVID H · 2003 to 2013
$102.6M
Novel Vaccine Technology for ChikungunyaR01AI093491 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI WEAVER, SCOTT C · 2011 to 2014
$3.2M
Mechanisms of sylvatic dengue emergenceR01AI069145 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI WEAVER, SCOTT C · 2008 to 2011
$2.5M
VEE Virus Infection on the Mosquito VectorR01AI071192 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI WEAVER, SCOTT C · 2008 to 2013
$2.0M
NIAID NIH HHS R01 AI069145NIAID NIH HHS R01-AI069145NIAID NIH HHS R01 AI071192NIAID NIH HHS R01-AI071192NIAID NIH HHS R01 AI093491NIAID NIH HHS R01AI093491NIAID NIH HHS U54 AI057156NIAID NIH HHS U54-AI057156
6 · The paper itself

Abstract

Alphaviruses are responsible for several medically important emerging diseases and are also significant veterinary pathogens. Due to the aerosol infectivity of some alphaviruses and their ability to cause severe, sometimes fatal neurologic diseases, they are also of biodefense importance. This review discusses the ecology, epidemiology and molecular virology of the alphaviruses, then focuses on three of the most important members of the genus: Venezuelan and eastern equine encephalitis and chikungunya viruses, with emphasis on their genetics and emergence mechanisms, and how current knowledge as well as gaps influence our ability to detect and determine the source of both natural outbreaks and potential use for bioterrorism. This article is one of a series in Antiviral Research on the genetic diversity of emerging viruses.

Indexed as

AlphavirusAlphavirus InfectionsAnimalsEcosystemEvolution, MolecularGenetics, PopulationHumansMolecular Epidemiology

Identifiers

PMID22522323
PMCPMC3737490
OpenAlexW2049676886

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.