ArticleVaccine2012
Protection of pigs against Taenia solium cysticercosis by immunization with novel recombinant antigens.
Article in Vaccine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 45 citations in OpenAlex.
- Successful immunization of naturally reared pigs against porcine cysticercosis with a recombinant oncosphere antigen vaccine.Veterinary parasitology · 2012Trial
- Effect of Community Health Education Intervention on Prevalence and Pig Farmers' Knowledge, Attitudes, and Practices Related to Porcine Cysticercosis in Selected Areas of Tanzania.Veterinary medicine international · 2025Article
- Insights into the diagnosis, vaccines, and control of Taenia solium, a zoonotic, neglected parasite.Parasites & vectors · 2023Review
- The Genomes of Two Strains ofFrontiers in cellular and infection microbiology · 2022Article
- Mimotope-based antigens as potential vaccine candidates in experimental murine cysticercosis.Parasitology · 2020Article
- Use of Veterinary Vaccines for Livestock as a Strategy to Control Foodborne Parasitic Diseases.Frontiers in cellular and infection microbiology · 2020Review
- Development of the multi-epitope chimeric antigen rqTSA-25 from Taenia saginata for serological diagnosis of bovine cysticercosis.PLoS neglected tropical diseases · 2018Article
- Metazoan Parasite Vaccines: Present Status and Future Prospects.Frontiers in cellular and infection microbiology · 2018Review
- Evaluation of activity of triclabendazole against Taenia solium metacestode in naturally infected pigs.Asian Pacific journal of tropical medicine · 2016Article
- Expression at a 20L scale and purification of the extracellular domain of the Schistosoma mansoni TSP-2 recombinant protein: a vaccine candidate for human intestinal schistosomiasis.Human vaccines & immunotherapeutics · 2013Article
- Neurocysticercosis: A disease of neglect.Tropical parasitology · 2013Review
- A review on diagnostic and preventive aspects of cystic echinococcosis and human cysticercosis.Tropical parasitology · 2012Article
- Isolated intramuscular cysticercosis: Clinicopathological features, diagnosis and management - A review.Journal of clinical orthopaedics and traumaReview
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recombinant antigens from the oncosphere stage of the parasite Taenia solium were expressed in Escherichia coli. The TSOL16, TSOL45-1A and TSOL45-1B recombinant antigens, each consisting of fibronectin type III (FnIII) domain S, were produced as fusion proteins with glutathione S-transferase (GST) and maltose binding protein (MBP). Groups of pigs were immunized twice with the GST fusions of the antigens and boosted a third time with the MBP fusions prior to receiving a challenge infection with T. solium eggs. The TSOL16 antigen was found to be capable of inducing high levels of immunity in pigs against a challenge infection with T. solium. Immunological investigations identified differences in immune responses in the pigs vaccinated with the various antigens. The results demonstrate that the TSOL16 antigen could be a valuable adjunct to current porcine vaccination approaches and may allow the further development of new vaccination strategies against T. solium cysticercosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.