Evidence map›Paper›PMID 22521139›Full record

ReviewCurrent opinion in immunology2012

Innate lymphoid cells: critical regulators of allergic inflammation and tissue repair in the lung.

Laurel A Monticelli, Gregory F Sonnenberg, David Artis

Abstract readReview
In one paragraph

Review in Current opinion in immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. The innate immune brakes of the lung.Frontiers in immunology · 2023
    Review
  6. Review
  7. The TOX subfamily: all-round players in the immune system.Clinical and experimental immunology · 2022
    Review
  8. Article
  9. Review
  10. Review
  11. Innate lymphoid cells are double-edged swords under the mucosal barrier.Journal of cellular and molecular medicine · 2021
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Airway innate lymphoid cells in the induction and regulation of allergy.Allergology international : official journal of the Japanese Society of Allergology · 2019
    Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Laurel A MonticelliDepartment of Microbiology and Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Gregory F Sonnenberg
David Artis

Funding

Regulation of protective immunity following enteric viral infectionU01AI095608 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI ARTIS, DAVID, SONNENBERG, GREGORY F · 2011 to 2025
$11.0M
PARASITOLOGY: MODERN APPROACHEST32AI007532 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HERBERT, DE'BROSKI R · 1998 to 2022
$5.0M
Innate immunity and inflammation following helminth infectionR01AI074878 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI ARTIS, DAVID · 2008 to 2019
$4.2M
Immuno-regulation of GI nematode infectionR01AI061570 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI ARTIS, DAVID · 2004 to 2013
$4.1M
Regulation and function of innate lymphoid cells in the gutR01AI095466 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI ARTIS, DAVID · 2011 to 2022
$3.7M
Regulation and function of innate lymphoid cells during influenza virus infectionR01AI102942 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI ARTIS, DAVID · 2013 to 2017
$2.1M
RELM-alpha regulation of hookworm-induced lung inflammationR01AI091759 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI NAIR, MEERA GOH · 2011 to 2015
$2.0M
Functional Biology of Intestinal Epithelial Cells in Food AllergyR21AI087990 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ARTIS, DAVID, ZIEGLER, STEVEN F · 2010 to 2011
$484k
Epithelial cell regulation of intestinal immune homeostasisR21AI083480 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ARTIS, DAVID · 2009 to 2010
$436k
NIAID NIH HHS AI061570NIAID NIH HHS AI074878NIAID NIH HHS AI087990NIAID NIH HHS AI091759NIAID NIH HHS AI095466NIAID NIH HHS AI095608NIAID NIH HHS R01 AI061570NIAID NIH HHS R01 AI074878NIAID NIH HHS R01 AI091759NIAID NIH HHS R01 AI095466NIAID NIH HHS R01 AI102942NIAID NIH HHS R21 AI083480NIAID NIH HHS R21 AI087990NIAID NIH HHS T32 AI007532NIAID NIH HHS T32-AI007532NIAID NIH HHS U01 AI095608
6 · The paper itself

Abstract

Maintenance of epithelial barrier function in the skin, respiratory tract and intestine is critical to limit exposure to commensal and pathogenic microbes and to maintain tissue homeostasis. Innate lymphoid cells (ILCs) are a recently recognized innate immune cell population that plays critical roles in host defense, regulation of inflammation and promotion of wound healing and tissue repair at barrier surfaces. In this review we discuss recent advances in the understanding of how ILC populations in the respiratory tract impact allergic airway inflammation and lung epithelial repair.

Indexed as

Immunity, InnateAnimalsAsthmaEpithelial CellsHumansLymphocytes

Identifiers

PMID22521139
PMCPMC3383398

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.