Evidence map›Paper›PMID 22521003›Full record

ArticleBMC psychiatry2012

Folate intake and depressive symptoms in Japanese workers considering SES and job stress factors: J-HOPE study.

Koichi Miyaki, Yixuan Song, Nay Chi Htun, Akizumi Tsutsumi, Hideki Hashimoto, Norito Kawakami, Masaya Takahashi, Akihito Shimazu, Akiomi Inoue, Sumiko Kurioka and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
8.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

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  14. Altered DNA methylation status of human brain derived neurotrophis factor gene could be useful as biomarker of depression.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2014
    Article
  15. Reliability, validity, and significance of assessment of sense of contribution in the workplace.International journal of environmental research and public health · 2014
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Koichi MiyakiDivision of Clinical Epidemiology, Department of Clinical Research and Informatics, National Center for Global Health and Medicine, Shinjuku-ku, Tokyo, Japan. miyaki-keio@umin.net
Yixuan Song
Nay Chi Htun
Akizumi Tsutsumi
Hideki Hashimoto
Norito Kawakami
Masaya Takahashi
Akihito Shimazu
Akiomi Inoue
Sumiko Kurioka
Takuro Shimbo
National Center for Global Health and Medicine · JPUniversity of Occupational and Environmental Health Japan · JPKitasato University · JPNational Institute of Occupational Safety and Health · JPTokyo Medical and Dental University · JPUniversity of Tokyo Health Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecently socioeconomic status (SES) and job stress index received more attention to affect mental health. Folate intake has been implicated to have negative association with depression. However, few studies were published for the evidence association together with the consideration of SES and job stress factors. The current study is a part of the Japanese study of Health, Occupation and Psychosocial factors related Equity (J-HOPE study) that focused on the association of social stratification and health and our objective was to clarify the association between folate intake and depressive symptoms in Japanese general workers.

methodsSubjects were 2266 workers in a Japanese nationwide company. SES and job stress factors were assessed by self-administered questionnaire. Folate intake was estimated by a validated, brief, self-administered diet history questionnaire. Depressive symptoms were measured by Kessler's K6 questionnaire. "Individuals with depressive symptoms" was defined as K6≥9 (in K6 score of 0-24 scoring system). Multiple logistic regression and linear regression model were used to evaluate the association between folate and depressive symptoms.

resultsSeveral SES factors (proportion of management positions, years of continuous employment, and annual household income) and folate intake were found to be significantly lower in the subjects with depressive symptom (SES factors: p < 0.001; folate intake: P = 0.001). There was an inverse, independent linear association between K6 score and folate intake after adjusting for age, sex, job stress scores (job strains, worksite supports), and SES factors (p = 0.010). The impact of folate intake on the prevalence of depressive symptom by a multiple logistic model was (ORs[95% CI]: 0.813 [0.664-0.994]; P =0.044).

conclusionsOur cross-sectional study suggested an inverse, independent relation of energy-adjusted folate intake with depression score and prevalence of depressive symptoms in Japanese workers, together with the consideration of SES and job stress factors.

Indexed as

DietFolic AcidSocial ClassAdultAsian PeopleCross-Sectional StudiesDepressionEmploymentFemaleHealth SurveysHumansJapanMaleMiddle AgedPrevalenceSocioeconomic FactorsFolic Acid

Identifiers

PMID22521003
PMCPMC3439709
OpenAlexW2047756651

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.