ArticleInternational journal of pediatrics2012
Laryngomalacia: disease presentation, spectrum, and management.
Article in International journal of pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04614974 (Initiation of Acid Suppression Therapy Prospective Outcomes for Laryngomalacia), which is not on this map. Cited by 42 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Initiation of Acid Suppression Therapy Prospective Outcomes for Laryngomalacia
Who cites it
42 citing papers in PubMed, 168 citations in OpenAlex.
- The effect of aryepiglottic fold release as an adjuvant step in surgery for Type I laryngomalacia.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2026Trial
- Acid Suppression in Mild-Moderate Laryngomalacia Without GERD: A Randomized Controlled Trial.The Laryngoscope · 2026Trial
- Neonatal airway emergency: congenital laryngeal myxoma.Journal of surgical case reports · 2026Article
- Transcervical Epiglottic Suspension for Severe Type III Laryngomalacia in Infants: Feasibility, Safety, and Effectiveness.Laryngoscope investigative otolaryngology · 2026Article
- Counseling Families on Long-Term Outcomes After Supraglottoplasty for Laryngomalacia: A Single-Surgeon Patient-Reported Outcome Cohort With 15-Year Follow-Up.Laryngoscope investigative otolaryngology · 2026Article
- Successful Treatment of Severe Laryngomalacia Due to Posterior Collapse of the Epiglottis by Correction of Glosso-Larynx (CGL): A Case Report.Children (Basel, Switzerland) · 2026Article
- Parental knowledge, attitudes, and practices regarding laryngomalacia in Saudi Arabia: a nationwide cross-sectional study.Frontiers in pediatrics · 2026Article
- Predicting surgical intervention in infants with laryngomalacia.International journal of pediatric otorhinolaryngology · 2025Article
- Article
- The anesthetic management of a child with ohtahara syndrome and severe stridor: a case report.BMC pediatrics · 2024Article
- Laryngomalacia and Obstructive Sleep Apnea in Children: From Diagnosis to Treatment.Children (Basel, Switzerland) · 2024Review
- The Prevalence of Dysphagia in Children with Laryngomalacia Pre and Postsupraglottoplasty: A Systematic Review with Meta-Analysis.International archives of otorhinolaryngology · 2024Review
- [New progress in diagnosis and treatment of congenital laryngomalacia in infants].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2023Article
- Caregiver Burnout in Pediatric Laryngomalacia: The Role of Clinical and Psychological Factors.Cureus · 2023Article
- Characteristics of Patients with Laryngomalacia: A Tertiary Referral Center Experience of 106 Cases.Diagnostics (Basel, Switzerland) · 2023Article
- Article
- Von Mises stress peak (VMSP) and laryngomalacia severity score (LSS) are extremely useful in the selection of treatment for laryngomalacia.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Article
- Surgical Candidacy for Management of Laryngomalacia: A Proposed Scoring System.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- Evaluation of vitamin D levels and biochemical markers in infants diagnosed with laryngomalacia.Turkish journal of medical sciences · 2023Article
- Dual Staged Supraglottoplasty for the Treatment of Trapdoor Epiglottis with Underlying Neurodegenerative Disease-Case report and Review of literature.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Laryngomalacia is the most common cause of stridor in newborns, affecting 45-75% of all infants with congenital stridor. The spectrum of disease presentation, progression, and outcomes is varied. Identifying symptoms and patient factors that influence disease severity helps predict outcomes. Findings. Infants with stridor who do not have significant feeding-related symptoms can be managed expectantly without intervention. Infants with stridor and feeding-related symptoms benefit from acid suppression treatment. Those with additional symptoms of aspiration, failure to thrive, and consequences of airway obstruction and hypoxia require surgical intervention. The presence of an additional level of airway obstruction worsens symptoms and has a 4.5x risk of requiring surgical intervention, usually supraglottoplasty. The presence of medical comorbidities predicts worse symptoms. Summary. Most with laryngomalacia will have mild-to-moderate symptoms and not require surgical intervention. Those with gastroesophageal reflux and/or laryngopharyngeal reflux have symptom improvement from acid suppression therapy. Those with severe enough disease to require supraglottoplasty will have minimal complications and good outcomes if multiple medical comorbidities are not present. Identifying patient factors that influence disease severity is an important aspect of care provided to infants with laryngomalacia.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.