Evidence map›Paper›PMID 22518167›Full record

ArticleObstetrics and gynecology international2012

Innovative oral treatments of uterine leiomyoma.

Mohamed Sabry, Ayman Al-Hendy

Open access · goldAbstract read
In one paragraph

Article in Obstetrics and gynecology international, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
8.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 73 citations in OpenAlex.

  1. Article
  2. Article
  3. Molecular and Cellular Insights into the Development of Uterine Fibroids.International journal of molecular sciences · 2021
    Review
  4. Article
  5. Article
  6. Article
  7. Current medical treatment of uterine fibroids.Obstetrics & gynecology science · 2018
    Review
  8. Review
  9. Minimally invasive procedures in the management of uterine fibroids.Przeglad menopauzalny = Menopause review · 2017
    Review
  10. Role of Transforming Growth Factor β in Uterine Fibroid Biology.International journal of molecular sciences · 2017
    Review
  11. Article
  12. Article
  13. Role of vitamin D in uterine fibroid biology.Fertility and sterility · 2015
    Review
  14. Article
  15. Review
  16. Review
  17. Intraobserver variability in fibroid size measurements: estimated effects on assessing fibroid growth.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2014
    Article
  18. Article
  19. Uterine fibroids: current perspectives.International journal of women's health · 2014
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Mohamed SabryCenter for Women Health Research (CWHR), Meharry Medical College, Nashville, TN 37208, USA.
Ayman Al-Hendy
Meharry Medical College · USSohag University · EG

Funding

Targeting Adenovirus for Gene Therapy of Uterine LeiomyomaR01HD046228 · NICHD · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI AL-HENDY, AYMAN · 2003 to 2014
$3.0M
NICHD NIH HHS R01 HD046228
6 · The paper itself

Abstract

Uterine fibroids (leiomyoma), the benign tumors of the uterine wall, are very common cause of morbidity in reproductive age women usually in the form of excessive vaginal bleeding, chronic pelvic pain, miscarriage and infertility. These tumors are the leading indication for hysterectomy in the United States. Uterine fibroids are about 4 times higher in blacks compared to whites and constitute a major health disparity challenge. The estimated cost of uterine fibroids is up to $34.4 billion annually. Additionally, women who suffer from this disease and desire to maintain their future fertility have very limited treatment choices. Currently, there is no effective long-term medicinal treatment for uterine fibroids. While surgery has traditionally been the gold standard for the treatment of uterine fibroids, there is growing interest towards orally administered medications for the management of leiomyoma-related symptoms. In this paper, we will discuss these promising innovative oral medical treatments in detail.

Identifiers

PMID22518167
PMCPMC3306913
OpenAlexW2059602130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.