ArticleAJNR. American journal of neuroradiology2012
Endovascular treatment of ruptured intracranial aneurysms: factors affecting midterm quality anatomic results: analysis in a prospective, multicenter series of patients (CLARITY).
Article in AJNR. American journal of neuroradiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02982200 (The MEDINA Study), which is not on this map. Cited by 38 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The MEDINA Study: Medina Embolization Device In Neurovascular Aneurysms Study - A Post Market Clinical Follow-up Study
Who cites it
38 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Aneurysmal recurrence and retreatment modalities after Woven EndoBridge (WEB) device implantation: A systematic review and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026Pooled it
- Retreatment rate and strategies for recurrent and residual aneurysms after Woven EndoBridge (WEB) treatment: a comprehensive systematic review and meta-analysis.Neurosurgical review · 2025Pooled it
- Pipeline embolization device for intracranial aneurysm: a systematic review.Clinical neuroradiology · 2012Pooled it
- Safety and efficacy of aneurysm treatment with WEB in the cumulative population of three prospective, multicenter series.Journal of neurointerventional surgery · 2018Trial
- HydroCoils Are Associated with Lower Angiographic Recurrence Rates Than Are Bare Platinum Coils in Treatment of "Difficult-to-Treat" Aneurysms: A Post Hoc Subgroup Analysis of the HELPS Trial.AJNR. American journal of neuroradiology · 2015Trial
- Device selection and clinical outcomes of adjunctive techniques for ruptured intracranial aneurysms: Insights from the JR-NET4 nationwide registry.Neuroradiology · 2026Article
- Y Stent-Assisted Coiling Technique for Bifurcation Aneurysms Using Double Neuroform® Stent: a Large Restrospective Series.Clinical neuroradiology · 2024Article
- Predictors of Aneurysm Obliteration in Patients Treated with the WEB Device: Results of a Multicenter Retrospective Study.AJNR. American journal of neuroradiology · 2024Article
- Comparison of Angiographic Outcomes of Woven EndoBridge and Balloon-Assisted Coiling for the Treatment of Ruptured Wide-Necked Aneurysms: A Multicentric Study.Stroke (Hoboken, N.J.) · 2024Article
- Initial Experiences with the Trenza Embolization Device for the Treatment of Wide-Neck Intracranial Aneurysms: A 12-Patient Case Series.AJNR. American journal of neuroradiology · 2024Observational
- Imaging follow-up strategy after endovascular treatment of Intracranial aneurysms: A literature review and guideline recommendations.Journal of cerebrovascular and endovascular neurosurgery · 2024Article
- WEB Treatment of Ruptured Intracranial Aneurysms: Long-Term Follow-up of a Single-Center Cohort of 100 Patients.AJNR. American journal of neuroradiology · 2023Article
- Patient and aneurysm factors associated with aneurysm recanalization after coiling.Journal of neurointerventional surgery · 2022Article
- Development and assessment of machine learning models for predicting recurrence risk after endovascular treatment in patients with intracranial aneurysms.Neurosurgical review · 2022Article
- Repeated Aneurysm Intervention.Advances and technical standards in neurosurgery · 2022Article
- Endovascular treatment of residual or recurrent intracranial aneurysms after surgical clipping.Journal of cerebrovascular and endovascular neurosurgery · 2021Article
- Wide neck bifurcation aneurysms: what is the optimal endovascular treatment?Journal of neurointerventional surgery · 2021Article
- Short- and midterm outcome of ruptured and unruptured intracerebral wide-necked aneurysms with microsurgical treatment.Scientific reports · 2021Article
- The safety and outcomes of acutely ruptured intracranial aneurysms with incomplete occlusion after coiling: a case-control study.BMC neurology · 2020Article
- Evaluation of clinical and anatomical outcome of staged stenting after acute coiling of ruptured intracranial aneurysms.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeRecanalization is 1 drawback of the EVT of intracranial aneurysms. An analysis of the factors affecting the midterm anatomic results after EVT of ruptured intracranial aneurysms in a large multicenter series (CLARITY) is presented. MATERIALS AND
methodsOf the 782 patients initially included in the CLARITY trial, 649 would theoretically undergo midterm follow-up examinations. Finally, 517/649 (79.7%) completed a midterm follow-up examination. Midterm anatomic results were independently and anonymously evaluated by 2 experienced neuroradiologists.
resultsIn univariate analysis, factors affecting the quality of midterm occlusion were the quality of the postoperative occlusion (P < .001), hypertension (P = .018), aneurysm size (P = .007), neck size (P = .005), and ICA location (P = .049). In multivariate analysis, 3 factors were associated with the quality of postoperative aneurysm occlusion: neck size (P = .003), use of the balloon remodeling technique (P = .031), and the quality of postoperative occlusion (P < .001). In univariate analysis, the evolution of aneurysm occlusion was affected by age (P = .024) and neck size (P = .041). In multivariate analysis, it was associated with the same factors: age (P = .025) and neck size (P = .043).
conclusionsAmong the many factors considered in this analysis, aneurysm neck size was identified as the single most important one in the quality of aneurysm occlusion at midterm follow-up after EVT. The present results suggest developing and evaluating new strategies of treatment and technique, especially for wide-neck aneurysms, with a focus on reinforcement and neoendothelialization at the level of the neck as objectives.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.