Evidence map›Paper›PMID 22517036›Full record

Trial reportJournal of perinatology : official journal of the California Perinatal Association2013

Parenteral amino acid intakes: possible influences of higher intakes on growth and bone status in preterm infants.

S Scattolin, P Gaio, M Betto, S Palatron, F De Terlizzi, F Intini, G Visintin, G Verlato

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Targeting optimal protein delivery in parenteral and enteral nutrition for preterm infants: a review of randomized, controlled trials.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Bone status in preterm infant: influences of different nutritional regimens and possible markers of bone disease.Journal of perinatology : official journal of the California Perinatal Association · 2016
    Article
  12. Aggressive Nutrition of the Preterm Infant.Current pediatrics reports · 2013
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

S ScattolinDepartment of Pediatrics, University of Padova, Padova, Italy.
P Gaio
M Betto
S Palatron
F De Terlizzi
F Intini
G Visintin
G Verlato

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the possible influences of amino acid (AA) intakes on growth and bone status in preterms. STUDY

designNewborns, weighing <1250 g, received standard (S) or higher (H) parenteral AA intakes (3 or 4 g kg(-1) per day). Anthropometry, biochemistry and quantitative ultrasound (metacarpus bone transmission time (mcBTT), in μs) were measured prospectively.

resultA total of 55 patients in group S and 60 in group H were studied. Significantly better growth rate was found in the H group during the study without signs of intolerance. We found a significant decrease in mcBTT from birth to 21 days in the H group; nonetheless, mcBTT at 36 weeks of gestational age significantly positively correlated with early AA and energy intakes. A significant positive correlation between mcBTT and lower limb length (LLL) at 21 days was found.

conclusionEarly higher AA intakes improved growth without short-term AA intolerance. Nutritional parameters could influence bone growth. LLL was the anthropometric parameter that best correlated to bone status.

Indexed as

Infant, Very Low Birth WeightAmino AcidsAnthropometryBone DensityBone DevelopmentEnergy IntakeFemaleFollow-Up StudiesHumansInfantInfant, NewbornInfant, Premature, DiseasesIntensive Care Units, NeonatalItalyMaleMetacarpusAmino Acids

Identifiers

PMID22517036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.