Evidence map›Paper›PMID 22516817›Full record

ArticlePlant signaling & behavior2012

NFXL2 modifies cuticle properties in Arabidopsis.

Janina Lisso, Florian Schröder, Jos H M Schippers, Carsten Müssig

Open access · bronzeAbstract read
In one paragraph

Article in Plant signaling & behavior, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Janina LissoLothar Willmitzer Department, Max Planck Institute of Molecular Plant Physiology, Universität Potsdam, Golm, Germany.
Florian Schröder
Jos H M Schippers
Carsten Müssig
Max Planck Institute of Molecular Plant Physiology · DEUniversity of Potsdam · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Loss of the Arabidopsis NFX1-LIKE2 (NFXL2) gene (At5g05660) results in elevated ABA levels, elevated hydrogen peroxide levels, reduced stomatal aperture, and enhanced drought stress tolerance. Introduction of the NFXL2-78 isoform into the nfxl2-1 mutant is largely sufficient for complementation of the phenotype. We show here that cuticular properties are altered in the nfxl2-1 mutant. The NFXL2-78 protein binds to the SHINE1 (SHN1), SHN2, SHN3, and BODYGUARD1 (BDG1) promoters and mediates weaker expression of these genes. The SHN AP2 domain transcription factors influence cuticle properties. Stronger SHN1, SHN2, and SHN3 expression in the nfxl2-1 mutant may cause altered cuticle properties including reduced stomatal density, and partly explain the enhanced drought stress tolerance. The BDG1 protein also controls cuticle development and is essential for osmotic stress regulation of ABA biosynthesis. Stronger BDG1 expression in nfxl2-1 plants may allow elevated ABA accumulation under drought stress. We conclude that the NFXL2-78 protein is part of a regulatory network that integrates the biosynthesis and action of ABA, ROS, and cuticle components.

Indexed as

Gene Expression Regulation, PlantGenes, PlantAbscisic AcidAdaptation, PhysiologicalArabidopsisArabidopsis ProteinsDroughtsOsmosisPlant EpidermisPlant StomataPromoter Regions, GeneticReactive Oxygen SpeciesStress, PhysiologicalTranscription FactorsWaterWaxesAbscisic AcidArabidopsis ProteinsNFXL2 protein, ArabidopsisReactive Oxygen SpeciesTranscription FactorsWaterWaxes

Identifiers

PMID22516817
PMCPMC3419017
OpenAlexW2060933632

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.