Evidence map›Paper›PMID 22516619›Full record

ReviewTrends in neurosciences2012

The Sturm und Drang of anabolic steroid use: angst, anxiety, and aggression.

Joseph G Oberlander, Leslie P Henderson

Abstract readReview
In one paragraph

Review in Trends in neurosciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
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  15. Article
  16. Article
  17. Review
  18. Psychosocial correlates of gap time to anabolic-androgenic steroid use.The International journal of eating disorders · 2018
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joseph G OberlanderDepartment of Physiology and Neurobiology, Dartmouth Medical School, Hanover, NH 03755, USA.
Leslie P Henderson

Funding

Steroid Regulation of Ion ChannelsR01DA014137 · NIDA · DARTMOUTH COLLEGE · PI HENDERSON, LESLIE P · 2001 to 2011
$3.0M
THE ROLE OF HORMONES IN HEALTH AND DISEASET32DK007508 · NIDDK · DARTMOUTH COLLEGE · PI NORTH, WILLIAM G · 1986 to 2011
$2.5M
Interactions of Anabolic Steroids and Stress Hormones in the ForebrainR03DA022716 · NIDA · DARTMOUTH COLLEGE · PI HENDERSON, LESLIE P · 2007 to 2008
$151k
NIDA NIH HHS DA014137NIDA NIH HHS DA022716NIDA NIH HHS R01 DA014137NIDA NIH HHS R03 DA022716NIDDK NIH HHS DK07508NIDDK NIH HHS T32 DK007508
6 · The paper itself

Abstract

Anabolic androgenic steroids (AAS) are illicitly administered to enhance athletic performance and body image. Although conferring positive actions on performance, steroid abuse is associated with changes in anxiety and aggression. AAS users are often keenly invested in understanding the biological actions of these drugs. Thus, mechanistic information on AAS actions is important not only for the biomedical community, but also for steroid users. Here we review findings from animal studies on the impact of AAS exposure on neural systems that are crucial for the production of anxiety and aggression, and compare the effects of the different classes of AAS and their potential signaling mechanisms, as well as context-, age- and sex-dependent aspects of their actions.

Indexed as

AggressionAnabolic AgentsAnxietyBrainFearHumansModels, NeurologicalPerformance-Enhancing SubstancesSteroidsAnabolic AgentsPerformance-Enhancing SubstancesSteroids

Identifiers

PMID22516619
PMCPMC4127319

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.