ArticleAmerican journal of public health2012
H1N1 influenza vaccination during pregnancy and fetal and neonatal outcomes.
Article in American journal of public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 10 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 10 syntheses or guidelines pooled it, 138 citations in OpenAlex.
- Pooled it
- Pooled it
- One "misunderstood" health issue: demonstrating and communicating the safety of influenza a vaccination in pregnancy: a systematic review and meta-analysis.BMC public health · 2021Pooled it
- The safety of inactivated influenza vaccines in pregnancy for birth outcomes: a systematic review.Human vaccines & immunotherapeutics · 2019Pooled it
- Vaccines for preventing influenza in healthy adults.The Cochrane database of systematic reviews · 2018Pooled it
- Guideline
- Guideline
- Community Mitigation Guidelines to Prevent Pandemic Influenza - United States, 2017.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2017Guideline
- Guideline for collection, analysis and presentation of safety data in clinical trials of vaccines in pregnant women.Vaccine · 2016Guideline
- Neonatal death: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data.Vaccine · 2016Guideline
- Altered response to A(H1N1)pnd09 vaccination in pregnant women: a single blinded randomized controlled trial.PloS one · 2013Trial
- Protecting pregnancy during pandemics: What recent outbreaks teach us.Human vaccines & immunotherapeutics · 2025Review
- Evaluating the Protective Effects of Influenza Vaccination in Pregnant Women and Their Infants: An Umbrella Review.Iranian journal of public health · 2025Review
- Article
- Assessing the Presence of IgG Antibodies against Influenza Viruses in Neonates after Maternal Vaccination and Factors That May Affect the Transplacental Transfer.Diseases (Basel, Switzerland) · 2023Article
- Knowledge and Attitudes of Healthcare Professionals Regarding Perinatal Influenza Vaccination during the COVID-19 Pandemic.Vaccines · 2023Article
- Factors Impacting Vaccine Uptake during Pregnancy: A Retrospective Analysis.International journal of MCH and AIDS · 2022Article
- Data Resource Profile: Better Outcomes Registry & Network (BORN) Ontario.International journal of epidemiology · 2021Article
- Prevalence of and factors associated with receipt of provider recommendation for influenza vaccination and uptake of influenza vaccination during pregnancy: cross-sectional study.BMC pregnancy and childbirth · 2021Article
- Safety of components and platforms of COVID-19 vaccines considered for use in pregnancy: A rapid review.Vaccine · 2021Review
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
objectivesWe evaluated the relationship between maternal H1N1 vaccination and fetal and neonatal outcomes among singleton births during the 2009-2010 H1N1 pandemic.
methodsWe used a population-based perinatal database in Ontario, Canada, to examine preterm birth (PTB), small-for-gestational-age (SGA) births, 5-minute Apgar score below 7, and fetal death via multivariable regression. We compared outcomes between women who did and did not receive an H1N1 vaccination during pregnancy.
resultsOf the 55,570 mothers with a singleton birth, 23,340 (42.0%) received an H1N1 vaccination during pregnancy. Vaccinated mothers were less likely to have an SGA infant based on the 10th (adjusted risk ratio [RR]=0.90; 95% confidence interval [CI]=0.85, 0.96) and 3rd (adjusted RR=0.81; 95% CI=0.72, 0.92) growth percentiles; PTB at less than 32 weeks' gestation (adjusted RR=0.73; 95% CI=0.58, 0.91) and fetal death (adjusted RR=0.66; 95% CI=0.47, 0.91) were also less likely among these women.
conclusionsOur results suggest that second- or third-trimester H1N1 vaccination was associated with improved fetal and neonatal outcomes during the recent pandemic. Our findings need to be confirmed in future studies with designs that can better overcome concerns regarding biased estimates of vaccine efficacy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.