Evidence map›Paper›PMID 22515575›Full record

ReviewInternational journal of dermatology2012

Trypanosoma cruzi infection: a review with emphasis on cutaneous manifestations.

Vagish Hemmige, Herbert Tanowitz, Aisha Sethi

Abstract readReview
In one paragraph

Review in International journal of dermatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
  2. Review
  3. Re: Chagas Disease (American Trypanosomiasis).Dermatology practical & conceptual · 2025
    Article
  4. Article
  5. Chagas Disease (American Trypanosomiasis).Dermatology practical & conceptual · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Chagas Disease.Annals of internal medicine · 2023
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. mBio · 2020
    Article
  18. Article
  19. Modulatory Effect ofFrontiers in cellular and infection microbiology · 2020
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Vagish HemmigeSection of Infectious Diseases and Global Health, University of Chicago Medical Center, Chicago, IL 60637, USA. vagish.hemmige@uchospitals..edu
Herbert Tanowitz
Aisha Sethi
University of Chicago Medical Center · USAlbert Einstein College of Medicine · US

Funding

T. cruzi: pathogenesis modulation by eicosanoidsR01AI076248 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI TANOWITZ, HERBERT BERNARD · 2008 to 2012
$2.3M
NIAID NIH HHS AI-076248NIAID NIH HHS R01 AI076248
6 · The paper itself

Abstract

Chagas disease, an infection caused by the protozoan Trypanosoma cruzi and transmitted by the Reduuvid insect vector, remains a major cause of morbidity in Central and South America over a century after its discovery in 1909. Though major advances in preventing the spread of this disease have been made in recent decades, millions of individuals remain chronically infected due to prior exposure to T. cruzi and are at risk for future complications from the disease. Dermatologic manifestations of acute infection may include localized swelling at the site of inoculation (chagoma), conjunctivitis (Romaña's sign), and a generalized morbilliform eruption (schizotrypanides). Reactivation of quiescent infection in immunocompromised hosts due to the acquired immunodeficiency syndrome or organ transplantation can present with fever and skin lesions including panniculitis. The widespread emigration of chronic carriers of T. cruzi to North America, Europe, and Australia makes it imperative that dermatologists worldwide be familiar with this entity to ensure proper diagnosis and treatment.

Indexed as

Trypanosoma cruziChagas DiseaseConjunctivitisHumansInsect Bites and StingsRecurrenceSkin Diseases, Parasitic

Identifiers

PMID22515575
PMCPMC3552304
OpenAlexW2112315489

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.