SynthesisBMC women's health2012
Treatment of endometriosis in different ethnic populations: a meta-analysis of two clinical trials.
Synthesis in BMC women's health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Prevalence of Common Gynecological Conditions in the Middle East: Systematic Review and Meta-Analysis.Frontiers in reproductive health · 2021Pooled it
- Is Scientific Medical Literature Related to Endometriosis Treatment Evidence-Based? A Systematic Review on Methodological Quality of Randomized Clinical Trials.Medicina (Kaunas, Lithuania) · 2019Pooled it
- Endometriosis as a highly relevant yet neglected gynecologic condition in Asian women.Endocrine connections · 2023Review
- Semantic and Population Analysis of the Genetic Targets Related to COVID-19 and Its Association with Genes and Diseases.Advances in experimental medicine and biology · 2023Article
- Impact of Long-Term Dienogest Therapy on Quality of Life in Asian Women with Endometriosis: the Prospective Non-Interventional Study ENVISIOeN.Reproductive sciences (Thousand Oaks, Calif.) · 2022Observational
- Circulating miRNAs Related to Epithelial-Mesenchymal Transitions (EMT) as the New Molecular Markers in Endometriosis.Current issues in molecular biology · 2021Review
- Review
- Ovarian Cancer Incidence in the Multi-Ethnic Asian City-State of Singapore 1968-2012.Asian Pacific journal of cancer prevention : APJCP · 2019Article
- Effectiveness of dienogest in improving quality of life in Asian women with endometriosis (ENVISIOeN): interim results from a prospective cohort study under real-life clinical practice.BMC women's health · 2019Article
- Variables Associated with Endometriosis-related Pain: A Pilot Study using a Visual Analogue Scale.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2019Article
- A review of the risk factors, genetics and treatment of endometriosis in Chinese women: a comparative update.Reproductive health · 2018Review
- New candidate therapeutic agents for endometrial cancer: potential for clinical practice (review).Oncology reports · 2013Review
- Characteristics of women with endometriosis from the USA and Puerto Rico.Journal of endometriosis and pelvic pain disordersArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Approaches to the treatment of endometriosis vary worldwide, but studies comparing endometriosis medications in different ethnic groups are rare. A systematic literature search identified two studies directly comparing dienogest (DNG) versus gonadotropin-releasing hormone (GnRH) analogues in European and Japanese populations. Meta-analysis of visual analogue scale scores revealed no heterogeneity in response between the trials, indicating equivalent efficacy of DNG and GnRH analogues for endometriosis-related pain across populations. DNG was significantly superior to GnRH analogues for bone mineral density change in both trials, but significant heterogeneity between the studies may indicate ethnic differences in physiology.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.