Evidence map›Paper›PMID 22514675›Full record

ArticlePloS one2012

Cellular basis for response diversity in the olfactory periphery.

Yuriy Bobkov, Il Park, Ill Park, Kirill Ukhanov, Jose Principe, Barry Ache

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Intermittency coding in the primary olfactory system: a neural substrate for olfactory scene analysis.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
    Article
  5. Article
  6. Mechanisms underlying odorant-induced and spontaneous calcium signals in olfactory receptor neurons of spiny lobsters, Panulirus argus.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2014
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

  • Erratum issued
    Park, Ill [corrected to Park, Il]
5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yuriy BobkovWhitney Laboratory, Center for Smell and Taste, and McKnight Brain Institute, University of Florida, Gainesville, Florida, United States of America. bobkov@whitney.ufl.edu
Il Park
Ill Park
Kirill Ukhanov
Jose Principe
Barry Ache
University of Florida · USTaste and Smell Clinic · USThe University of Texas at Austin · US

Funding

MULTIPLE PATHWAYS IN OLFACTORY TRANSDUCTIONR01DC001655 · NIDCD · UNIVERSITY OF FLORIDA · PI ACHE, BARRY W. · 1992 to 2010
$3.0M
Strategies for encoding odor informationR21DC011859 · NIDCD · UNIVERSITY OF FLORIDA · PI ACHE, BARRY W. · 2011 to 2012
$403k
NIDCD NIH HHS DC001655NIDCD NIH HHS DC011859NIDCD NIH HHS R01 DC001655NIDCD NIH HHS R21 DC011859
6 · The paper itself

Abstract

An emerging idea in olfaction is that temporal coding of odor specificity can be intrinsic to the primary olfactory receptor neurons (ORNs). As a first step towards understanding whether lobster ORNs are capable of generating odor-specific temporal activity and what mechanisms underlie any such heterogeneity in discharge pattern, we characterized different patterns of activity in lobster ORNs individually and ensemble using patch-clamp recording and calcium imaging. We demonstrate that lobster ORNs show tonic excitation, tonic inhibition, phaso-tonic excitation, and bursting, and that these patterns are faithfully reflected in the calcium signal. We then demonstrate that the various dynamic patterns of response are inherent in the cells, and that this inherent heterogeneity is largely determined by heterogeneity in the underlying intrinsic conductances.

Indexed as

AnimalsCalciumDecapodaElectrophysiologyOlfactory Receptor NeuronsCalcium

Identifiers

PMID22514675
PMCPMC3325939
OpenAlexW2055525215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.