SynthesisThe Cochrane database of systematic reviews2012
Glucocorticoids for the treatment of anaphylaxis.
Synthesis in The Cochrane database of systematic reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.
- Systematic review of outcome measures in trials of pediatric anaphylaxis treatment.BMC pediatrics · 2014Pooled it
- Life-Threatening Anaphylaxis due to Cerebrolysin®.Case reports in neurological medicine · 2024Article
- Anaphylaxis management in a French pediatric emergency department: Lessons from the ANA-PED study.Clinical and translational allergy · 2023Article
- Anaphylaxis is rare due to CoronaVac in a population of healthcare workers.Asia Pacific allergy · 2022Article
- Hypertensive and Hypotensive Emergencies in Interventional Radiology.Seminars in interventional radiology · 2022Review
- Emergency treatment of anaphylaxis: concise clinical guidance.Clinical medicine (London, England) · 2022Article
- A Clinical Practice Guideline for the Emergency Management of Anaphylaxis (2020).Frontiers in pharmacology · 2022Article
- Evidence update for the treatment of anaphylaxis.Resuscitation · 2021Review
- An Updated Review of the Molecular Mechanisms in Drug Hypersensitivity.Journal of immunology research · 2018Review
- Anaphylaxis across two Canadian pediatric centers: evaluating management disparities.Journal of asthma and allergy · 2017Article
- Anaphylaxis in the acute care setting.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2014Review
- International consensus on (ICON) anaphylaxis.The World Allergy Organization journal · 2014Article
- Scratching the surface of allergic transfusion reactions.Transfusion · 2013Review
- Antiallergic and Antiarthritic Effects of Stem Bark Extract of Glyphaea brevis (Spreng) Monachino (Tiliaceae) in Murine Models.ISRN pharmacology · 2013Article
- From the Children's Oncology Group: Evidence-Based Recommendations for PEG-Asparaginase Nurse Monitoring, Hypersensitivity Reaction Management, and Patient/Family Education.Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology NursesReview
Corrections and comments
- Update of
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnaphylaxis is a serious hypersensitivity reaction that is rapid in onset and may result in death. Anaphylaxis guidelines recommend glucocorticoids for the treatment of people experiencing anaphylaxis.
objectivesWe sought to assess the benefits and harms of glucocorticoid treatment during episodes of anaphylaxis. SEARCH
methodsIn our previous version we searched the literature until September 2009. In this version we searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2011, Issue 3), MEDLINE (Ovid) (1956 to September 2011), EMBASE (Ovid) (1982 to September 2011), CINAHL (EBSCOhost) (to September 2011). We also searched the UK National Research Register and websites listing ongoing trials, and contacted international experts in anaphylaxis in an attempt to locate unpublished material. SELECTION CRITERIA: We planned to include randomized and quasi-randomized controlled trials comparing glucocorticoids with any control (either placebo, adrenaline (epinephrine), an antihistamine, or any combination of these). DATA COLLECTION AND ANALYSIS: Two authors independently assessed articles for inclusion. MAIN
resultsWe found no studies that satisfied the inclusion criteria. AUTHORS'
conclusionsWe are, based on this review, unable to make any recommendations for the use of glucocorticoids in the treatment of anaphylaxis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.