ArticleBiomacromolecules2012
Suppressing surface reconstruction of superhydrophobic PDMS using a superhydrophilic zwitterionic polymer.
Article in Biomacromolecules, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Long-Term Hydrophilic, Anti-Clotting, and Anti-Fibrotic Dynamic Covalent Silicone-Based Biomaterials.Advanced healthcare materials · 2026Article
- Article
- Surface-segregating zwitterionic copolymers to control poly(dimethylsiloxane) surface chemistry.Journal of materials chemistry. B · 2023Article
- Controlled swelling of biomaterial devices for improved antifouling polymer coatings.Scientific reports · 2023Article
- Perspectives and trends in advanced optical and electrochemical biosensors based on engineered peptides.Mikrochimica acta · 2023Review
- Investigating the effect of phospholipids on droplet formation and surface property evolution in microfluidic devices for droplet interface bilayer (DIB) formation.Biomicrofluidics · 2022Article
- Simultaneous Realization of Superoleophobicity and Strong Substrate Adhesion in Water via a Unique Segment Orientation Mechanism.Advanced materials (Deerfield Beach, Fla.) · 2022Article
- Amphiphilic Polyphosphonate Copolymers as New Additives for PDMS-Based Antifouling Coatings.Polymers · 2021Article
- Photograftable Zwitterionic Coatings PreventACS applied bio materials · 2021Article
- Anti-Biofouling Polymers with Special Surface Wettability for Biomedical Applications.Frontiers in bioengineering and biotechnology · 2021Review
- Strontium-releasing mesoporous bioactive glasses with anti-adhesive zwitterionic surface as advanced biomaterials for bone tissue regeneration.Journal of colloid and interface science · 2020Article
- Antifouling Photograftable Zwitterionic Coatings on PDMS Substrates.Langmuir : the ACS journal of surfaces and colloids · 2019Article
- Characterization of covalent crosslinking strategies for synthesizing DNA-based bioconjugates.Journal of biological engineering · 2019Article
- The Relationship between Bulk Silicone and Benzophenone-Initiated Hydrogel Coating Properties.Polymers · 2018Article
- Superhydrophobic PolymerizedACS omega · 2018Article
- Superior LSPR substrates based on electromagnetic decoupling for on-a-chip high-throughput label-free biosensing.Light, science & applications · 2017Article
- Experimental design and analysis of activators regenerated by electron transfer-atom transfer radical polymerization experimental conditions for grafting sodium styrene sulfonate from titanium substrates.Journal of vacuum science & technology. A, Vacuum, surfaces, and films : an official journal of the American Vacuum Society · 2015Article
- Green materials science and engineering reduces biofouling: approaches for medical and membrane-based technologies.Frontiers in microbiology · 2015Review
- Surface initiated atom transfer radical polymerization grafting of sodium styrene sulfonate from titanium and silicon substrates.Journal of vacuum science & technology. A, Vacuum, surfaces, and films : an official journal of the American Vacuum Society · 2013Article
- Functionalization of polydimethylsiloxane membranes to be used in the production of voice prostheses.Science and technology of advanced materials · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Poly(dimethyl siloxane) (PDMS) is extensively used for biomedical applications due to its low cost, ease of fabrication, high durability and flexibility, oxygen permeability, and self-healing properties. PDMS, however, has some significant drawbacks. PDMS endures unacceptably high levels of nonspecific protein fouling when used with biological samples due to its superhydrophobic characteristics. Unfortunately, conventional surface modification methods do not work for PDMS due to its low glass transition temperature. This phenomenon has been well-known for years as "hydrophobic regeneration". For the same reason, it is also very difficult to bring functionalities onto PDMS surfaces. Herein, we demonstrate how a superhydrophilic zwitterionic material, poly(carboxybetaine methacrylate) (pCBMA), can provide a highly stable coating with long-term stabilty due to the sharp contrast in hydrophobicity between pCBMA and PDMS. This material is able to suppress nonspecific protein adsorption in complex media and functionalize desired biomolecules needed in applications, such as diagnostics, without sacrificing its nonfouling characteristics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.