Is it time for medicine-based evidence?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Effect of age on the effectiveness of the first-line standard of care treatment in patients with metastatic colorectal cancer: systematic review of observational studies.Journal of cancer research and clinical oncology · 2019
   Pooled it
2. Medicine's 'Basic' Mistake: How the Molecular Revolution Displaced an Entire Category of Inquiry.Journal of evaluation in clinical practice · 2026
   Review
3. Finding purpose: Integrated latent profile and machine learning analyses identify purpose in life as an important predictor of high-functioning recovery after alcohol treatment.Addictive behaviors · 2025
   Article
4. Pragmatic Comparative Effectiveness Trials and Learning Health Systems in Pain Medicine: Opportunities and Challenges.Anesthesiology clinics · 2023
   Review
5. Diabetes-related foot disease research in Aotearoa New Zealand: a bibliometric analysis (1970-2020).Journal of foot and ankle research · 2022
   Article
6. Schizophrenic patients with type 2 diabetes: An 8-year population-based observational study.PloS one · 2021
   Observational
7. While modern medicine evolves continuously, evidence-based research methodology remains: how register studies should be interpreted and appreciated.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2017
   Article
8. Feasibility of a quality improvement strategy integrating psychosocial care into 28 medical cancer centers (HuCare project).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016
   Article
9. Comparative effectiveness of cardiac resynchronization therapy in combination with implantable defibrillator in patients with heart failure and wide QRS duration.The American journal of cardiology · 2014
   Article
10. Comparative effectiveness research.AJNR. American journal of neuroradiology · 2014
    Article
11. Randomised controlled trials and population-based observational research: partners in the evolution of medical evidence.British journal of cancer · 2014
    Article
12. Cost-effectiveness data: Are neurologists in practice equipped to interpret them?Neurology. Clinical practice · 2013
    Article
13. The use of clinical trials in comparative effectiveness research on mental health.Journal of clinical epidemiology · 2013
    Article
14. Impact of a modified data capture period on Liu comorbidity index scores in Medicare enrollees initiating chronic dialysis.BMC nephrology · 2013
    Article
15. Patient-centered, comparative effectiveness of esophageal cancer screening: protocol for a comparative effectiveness research study to inform guidelines for evidence-based approach to screening and surveillance endoscopy.BMC health services research · 2012
    Article
16. Association of ustekinumab and briakinumab with major adverse cardiovascular events: An appraisal of meta-analyses and industry sponsored pooled analyses to date.Dermato-endocrinology · 2012
    Article

Corrections and comments

• Comment on
  Carboplatin and paclitaxel with vs without bevacizumab in older patients with advanced non-small cell lung cancer.2012
• Comment on
  Association between helicopter vs ground emergency medical services and survival for adults with major trauma.2012
• Comment on
  Intensity-modulated radiation therapy, proton therapy, or conformal radiation therapy and morbidity and disease control in localized prostate cancer.2012
• Comment on
  Comparison of long-term survival after open vs endovascular repair of intact abdominal aortic aneurysm among Medicare beneficiaries.2012
• Comment on
  Long-term survival following partial vs radical nephrectomy among older patients with early-stage kidney cancer.2012

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as