Evidence map›Paper›PMID 22511134›Full record

ArticleCritical care medicine2012

Trends in the incidence of noncardiogenic acute respiratory failure: the role of race.

Colin R Cooke, Sara E Erickson, Mark D Eisner, Greg S Martin

Abstract read
In one paragraph

Article in Critical care medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
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  17. Adjuvant Therapies for ARDS: Not Ready for Prime Time?Annals of the American Thoracic Society · 2017
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Colin R CookeDivision of Pulmonary and Critical Care Medicine, Robert Wood Johnson Foundation Clinical Scholars Program, Center for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI, USA. cookecr@umich.edu
Sara E Erickson
Mark D Eisner
Greg S Martin
University of Michigan–Ann Arbor · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025008 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$29.0M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalKL2TR000455 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$2.9M
Atlanta Clinical and Translational Science Institute (KL2)KL2RR025009 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$2.9M
Phase III Study Comparing Albumin and Hetastarch Therapy in Acute Lung InjuryR01FD003440 · FDA · EMORY UNIVERSITY · PI MARTIN, GREGORY S · 2008 to 2013
$1.1M
HIGH-DOSE VITAMIN D AND ANTIMICROBIAL PEPTIDE EXPRESSION IN LUNG FAILURER21HL110044 · NHLBI · EMORY UNIVERSITY · PI MARTIN, GREGORY S, ZIEGLER, THOMAS R · 2011 to 2012
$355k
FDA HHS FD R01-003440NCATS NIH HHS KL2 TR000455NCATS NIH HHS UL1 TR000454NCRR NIH HHS KL2 RR-025009NCRR NIH HHS KL2 RR025009NCRR NIH HHS UL1 RR025008NHLBI NIH HHS R21 HL110044
6 · The paper itself

Abstract

objectiveWe sought to examine trends in the race-specific incidence of acute respiratory failure in the United States.

designRetrospective cohort study.

settingWe used the National Hospital Discharge Survey database (1992-2007), an annual survey of approximately 500 hospitals weighted to provide national hospitalization estimates. PATIENTS: All incident cases of noncardiogenic acute respiratory failure hospitalized in the United States.

interventionsNone. MEASUREMENTS AND MAIN

resultsWe identified noncardiogenic acute respiratory failure by the presence of International Classification of Diseases, Ninth Revision, codes for respiratory failure or pulmonary edema (518.4, 518.5, 518.81, and 518.82) and mechanical ventilation (96.7×), excluding congestive heart failure. Incidence rates were calculated using yearly census estimates standardized to the age and sex distribution of the 2000 census population. Annual cases of noncardiogenic acute respiratory failure increased from 86,755 in 1992 to 323,474 in 2007. Noncardiogenic acute respiratory failure among black Americans increased from 56.4 (95% confidence interval 39.7-73.1) to 143.8 (95% confidence interval 123.8-163.8) cases per 100,000 in 1992 and 2007, respectively. Among white Americans, the incidence of noncardiogenic acute respiratory failure increased from 31.2 (95% confidence interval 26.2-36.5) to 94.0 (95% confidence interval 86.7-101.2) cases per 100,000 in 1992 and 2007, respectively. The average annual incidence of noncardiogenic acute respiratory failure over the entire study period was 95.1 (95% confidence interval 93.9-96.4) cases per 100,000 for black Americans compared to 66.5 (95% confidence interval 65.8-67.2) cases per 100,000 for white Americans (rate ratio 1.43, 95% confidence interval 1.42-1.44). Overall in-hospital mortality was greater for other-race Americans, but only among patients with two or more organ failures (57% [95% confidence interval 56%-59%] for other race, 51% [95% confidence interval 50%-52%] for white, 50% [95% confidence interval 49%-51%] for black).

conclusionsThe incidence of noncardiogenic acute respiratory failure in the United States increased between 1992 and 2007. Black and other-race Americans are at greater risk of developing noncardiogenic acute respiratory failure compared to white Americans.

Indexed as

Acute DiseaseAge FactorsBlack or African AmericanBlack PeopleFemaleHealth Status DisparitiesHumansIncidenceMaleMiddle AgedRacial GroupsRespiratory InsufficiencyRetrospective StudiesRisk FactorsSex FactorsUnited States

Identifiers

PMID22511134
PMCPMC3329645
OpenAlexW2072349142

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.