ReviewClinical obstetrics and gynecology2012
Serum biomarkers for detecting ectopic pregnancy.
Review in Clinical obstetrics and gynecology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05591599 (Diagnostic Value of Calponin 2 in Identifying Tubal Pregnancies), which is not on this map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Diagnostic Value of Calponin 2 in Identifying Tubal Pregnancies
Who cites it
21 citing papers in PubMed.
- The diagnosis and management of extrauterine and uterine ectopic pregnancy.Human reproduction update · 2026Review
- Hormonal and electrolyte predictors for methotrexate versus surgery in ectopic pregnancy.PloS one · 2025Article
- Untargeted Metabolomic Biomarker Discovery for the Detection of Ectopic Pregnancy.International journal of molecular sciences · 2024Article
- Can failure be predicted in methotrexate treatment with the modified parameter?Archives of gynecology and obstetrics · 2024Article
- Lactate plasma level as a potential biomarker in early diagnosis of ectopic pregnancy: A case-control survey.Health science reports · 2023Article
- Copper/Zinc Ratio Can Be a Marker to Diagnose Ectopic Pregnancy and Is Associated with the Oxidative Stress Status of Ectopic Pregnancy Cases.Biological trace element research · 2021Article
- Metabolomic identification of novel diagnostic biomarkers in ectopic pregnancy.Metabolomics : Official journal of the Metabolomic Society · 2019Article
- B cell activation factor (BAFF) induces inflammation in the human fallopian tube leading to tubal pregnancy.BMC pregnancy and childbirth · 2019Article
- Congenital Transmission ofFrontiers in microbiology · 2019Review
- Methotrexate Therapy for Ectopic Pregnancies: A Tertiary Center Experience.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2018Article
- Developing a deeper insight into reproductive biomarkers.Clinical and experimental reproductive medicine · 2017Review
- Ectopic pregnancy: exploration of its global research architecture using density-equalising mapping and socioeconomic benchmarks.BMJ open · 2017Article
- No increase in free fetal DNA level in ectopic pregnancy: A preliminary study.Turkish journal of obstetrics and gynecology · 2017Article
- Tale of 2 pregnancies: Heterotopic pregnancy in a spontaneous cycle.Canadian family physician Medecin de famille canadien · 2016Article
- Virtual High-Throughput Screening To Identify Novel Activin Antagonists.Journal of medicinal chemistry · 2015Article
- The value of ratio of hCG, progesterone in local blood of pregnancy location versus venous blood in the diagnosis of ectopic pregnancy.International journal of clinical and experimental medicine · 2015Article
- Incidence, diagnosis and management of tubal and nontubal ectopic pregnancies: a review.Fertility research and practice · 2015Review
- Role of activins in embryo implantation and diagnosis of ectopic pregnancy: a review.Reproductive biology and endocrinology : RB&E · 2014Article
- Maternal Serum Macrophage Inhibitory Cytokine-1 as a Biomarker for Ectopic Pregnancy in Women with a Pregnancy of Unknown Location.PloS one · 2013Article
- Role of various complete blood count parameters in predicting the success of single-dose Methotrexate in treating ectopic pregnancy.Pakistan journal of medical sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Unless an ectopic pregnancy is visible by ultrasound, diagnosis can be a challenge. Differentiating ectopic pregnancies from intrauterine pregnancies can be impossible without intervention or follow-up. This poses a clinical dilemma to the practitioner given the inherent danger to the mother of tubal rupture of an ectopic pregnancy versus the fear of intervening in the case of a desired pregnancy without certainty of diagnosis. Early diagnostic modalities are clearly lacking, and serum biomarkers are currently being investigated as a solution to need for a rapid and accurate test for ectopic pregnancy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.